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Prediction of liver cirrhosis, using diagnostic imaging tools 被引量:9

Prediction of liver cirrhosis, using diagnostic imaging tools
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摘要 Early diagnosis of liver cirrhosis is important. Ultrasoundguided liver biopsy is the gold standard for diagnosis of liver cirrhosis. However, its invasiveness and sampling bias limit the applicability of the method. Basic imaging for the diagnosis of liver cirrhosis has developed over the last few decades, enabling early detection of morphological changes of the liver by ultrasonography(US), computed tomography, and magnetic resonance imaging(MRI). They are also accurate diagnostic methods for advanced liver cirrhosis, for which early diagnosis is difficult. There are a number of ways to compensate for this difficulty, including texture analysis to more closely identify the homogeneity of hepatic parenchyma, elastography to measure the stiffness and elasticity of the liver, and perfusion studies to determine the blood flow volume, transit time, and velocity. Amongst these methods, elastography using US and MRI was found to be slightly easier, faster, and able to provide an accurate diagnosis. Early diagnosis of liver cirrhosis using MRI or US elastography is therefore a realistic alternative, but further research is still needed. Early diagnosis of liver cirrhosis is important. Ultrasoundguidedliver biopsy is the gold standard for diagnosis ofliver cirrhosis. However, its invasiveness and samplingbias limit the applicability of the method. Basic imagingfor the diagnosis of liver cirrhosis has developed overthe last few decades, enabling early detection ofmorphological changes of the liver by ultrasonography(US), computed tomography, and magnetic resonanceimaging (MRI). They are also accurate diagnosticmethods for advanced liver cirrhosis, for which earlydiagnosis is difficult. There are a number of ways tocompensate for this difficulty, including texture analysisto more closely identify the homogeneity of hepaticparenchyma, elastography to measure the stiffness andelasticity of the liver, and perfusion studies to determinethe blood flow volume, transit time, and velocity.Amongst these methods, elastography using US andMRI was found to be slightly easier, faster, and able toprovide an accurate diagnosis. Early diagnosis of livercirrhosis using MRI or US elastography is therefore arealistic alternative, but further research is still needed.
出处 《World Journal of Hepatology》 CAS 2015年第17期2069-2079,共11页 世界肝病学杂志(英文版)(电子版)
关键词 Liver fibrosis ULTRASONOGRAPHY COMPUTEDTOMOGRAPHY Magnetic resonance IMAGING Magneticresonance ELASTOGRAPHY SONOELASTOGRAPHY Acousticradiation force impulse IMAGING Liver fibrosis Ultrasonography Computed tomography Magnetic resonance imaging Magnetic resonance elastography Sonoelastography Acoustic radiation force impulse imaging
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