摘要
目的:观察去甲肾上腺素(NE)对感染性休克患者丙泊酚麻醉期间维持血液动力学稳定的疗效。方法:将2011年3月至2014年8月应用手术治疗的感染性休克患者28例随机分为NE组(n=14)和多巴胺(DA)组(n=14),丙泊酚麻醉期间分别应用NE和DA维持血液动力学稳定,比较两组在入室时(T0)、麻醉诱导期(T1)、气管插管后(T2)、拔管后(T3)的平均动脉压(MAP)和心率(HR)。结果:DA和NE均能有效预防和治疗感染性休克患者丙泊酚麻醉期间各时点的低血压,但NE组在T1、T2、T3时点的HR明显低于DA组(P<0.05)。结论 :NE对感染性休克患者丙泊酚麻醉期间可有效维持血液动力学稳定,提高感染性休克患者手术期间的抢救成功率。
Objective ：To observe the clinical effect of hemodynamic on patients with septic shock during propofol anesthesia used norepinephrine（NE）. Methods ： 28 patients with septic shock treated by operation were randomly divided into NE group（n=14） and dopamine（DA） group（n=14） used NE and DA to maintain stable hemodynamics prospectively during propofol anesthesia. The MAP and HR were compared between the two groups at before the anesthesia（T0）,anesthesia induction period（T1）, after tracheal intubation（T2）and tracheal extubation（T3）. Results ：DA and NE can prevent and treat patients with septic shock during propofol anesthesia hypotension,but the HR at T1,T2 and T3 in NE group were significantly lower than those in the DA group（P〈0.05）.Conclusions：NE can effectively maintain the hemodynamic stability and improve the operation rescue success rate on patients with septic shock during propofol anesthesia.
出处
《岭南急诊医学杂志》
2015年第3期209-210,216,共3页
Lingnan Journal of Emergency Medicine
