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妊娠合并甲状腺功能减退和亚临床甲状腺功能减退筛查的临床意义 被引量:18

Clinical values of hypothyroidism and subclinical hypothyroidism screening in pregnancy
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摘要 回顾性分析妊娠合并甲状腺功能减退症(甲减,36例)、亚临床甲减(103例)患者的临床资料,并对其妊娠结局、胎儿情况进行分析.妊娠合并甲减孕妇流产(11.1%)、早产(8.3%)、子痫前期(11.1%)、妊娠期糖尿病(13.9%)、贫血(16.7%)、胎儿宫内生长受限(5.6%)及胎儿窘迫率(8.3%),高于139例正常对照者(2.9%、1.4%、1.4%、2.2%、4.3%、0.0%和3.6%),差异有统计学意义(均P <0.05).提示,妊娠不良结局的发生与甲减关系密切,在孕期进行甲状腺功能筛查十分必要,以改善不良妊娠结局. To explore the significance of hypothyroidism and subclinical hypothyroidism screening in pregnancy.A total of 278 pregnant women were divided into three groups of clinical hypothyroidism (n =36),subclinical hypothyroidism (n =103) and normal control (n =139).Their clinical profiles,pregnancy outcomes and fetal status were analyzed.The incidences of abortion (11.1%),premature delivery (8.3%),preeclampsia (11.1%),gestational diabetes mellitus (GDM,13.9%),anemia (16.7%),fetal distress (8.3%) and fetal growth retardation (FGR,5.6%) in clinical hypothyroidism group were higher than those in normal control group (2.9%,1.4%,1.4%,2.2%,4.3%,0.0% and 3.6%).And the differences were statistically significant (P < 0.05).The incidence of adverse pregnancy had a significant correlation with hypothyroidism in pregnant women.Therefore screening of thyroid functions is essential for improving pregnancy outcomes of pregnant women with hypothyroidism.
作者 宋春红
出处 《中华全科医师杂志》 2015年第8期620-622,共3页 Chinese Journal of General Practitioners
关键词 甲状腺功能减退症 妊娠 Hypothyroidism Pregnancy
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