摘要
目的探讨18F-FDG PET/CT显像对引起胆道梗阻的恶性肿瘤的诊断价值。方法搜集并回顾性分析39例经病理证实因恶性肿瘤引起梗阻性黄疸患者的18F-FDG PET/CT显像资料;通过半定量法测定的最大标准摄取值(SUVmax)对图像进行分析,定性以局部区域放射性浓聚为依据,以SUVmax≥2.5作为诊断恶性肿瘤的依据。结果18F-FDG PET/CT诊断恶性胆道梗阻性疾病的定性符合率为97.4%(38/39),定位符合率为92.3%(36/39)。本组38例PET-CT显像的引起胆道梗阻的恶性肿瘤大小为(3.08±1.32)cm,SUVmax为5.12±1.74,两者Pearson相关系数为0.511,P=0.001。对肝内胆管细胞癌(14例)、肝外胆管癌(10例)、胰头癌(8例)、胆囊癌(6例)的病灶大小及SUVmax分别进行单因素方差分析,各组大小比较F=4.401,P=0.01;SUVmax比较F=1.519,P=0.227。结论18F-FDG PET/CT显像对引起胆道梗阻的恶性肿瘤的定性及定位诊断有较高的准确率,SUVmax与病灶大小呈正相关,与病理类型无关。
Objective To investigate the value of18F-FDG PET / CT in diagnosing biliary tract obstruction with malignant tumors.Methods18F-FDG PET / CT appearance of 39 cases with proven pulmonary benign lesions were retrospectively reviewed.The images were analyzed through the semi-quantitative method.Judgment standard of malignant tumor was based on local area radioactive distribution strength together with SUVmax ≥2.5.Results Coincidence rate of qualitative diagnosis and locating diagnosis of18F-FDG PET / CT in biliary tract obstruction with malignant tumors was 97.4%（38 /39）and 92.3%（36 /39） respectively.The size（represented in diameter） of the malignant tumor causing biliary tract obstruction displayed in PET-CT was（3.08 ± 1.32） cm,and SUVmax of which was 5.12 ± 1.74.Pearson correlation coefficient of both was 0.511（P = 0.001）.The size and SUVmax of intrahepatic cholangiocarcinoma（n = 14）,extrahepatic cholangiocarcinoma（n = 10）,pancreatic head carcinoma（n = 8） and gallbladder carcinoma（n = 6） displayed in PET / CTwas compared by oneway analysis of variance respectively.The result in comparison of size was F = 4.401,P = 0.01,and in comparison of SUVmax was F = 1.519,P = 0.227.Conclusion18F-FDG PET / CT has very high accuracy rate in locating and qualitative d diagnosing biliary tract obstruction with malignant tumors.SUVmax is positively related to the lesion size,and has no relation with the pathological type.
出处
《临床放射学杂志》
CSCD
北大核心
2015年第7期1093-1096,共4页
Journal of Clinical Radiology
