摘要
全反式维甲酸是抑制肝细胞损伤的关键物质之一,他在肝细胞损伤的发生发展过程中起着重要作用.近年来,大量研究表明,全反式维甲酸可以抑制肝细胞的凋亡、促进肝细胞的恢复.而且研究者们提出了使用全反式维甲酸抑制肝细胞损伤治疗的新方法,在肝癌治疗及病毒性肝炎治疗的研究方面取得了可喜的进展.本文将以全反式维甲酸为切入点,对全反式维甲酸抑制肝细胞损伤的作用机制作一综述.
All-trans retinoic acid（ATRA） is one of the key compounds in inhibiting liver injury,and it plays an important role in the occurrence and development of liver injury.In recent years,numerous studies have shown that ATRA can inhibit the apoptosis of hepatocytes and promote the recovery of liver cells.Researchers have proposed using ATRA to inhibit liver injury,and great progress has been made in using such compound to treat liver cancer and viral hepatitis.This article reviews the mechanism of ATRA for inhibiting liver injury.
出处
《世界华人消化杂志》
CAS
2015年第19期3081-3085,共5页
World Chinese Journal of Digestology
基金
重庆医科大学附属永川医院青年基金资助项目
No.YJQN201424~~
关键词
全反式维甲酸
肝损伤
凋亡
All-trans retinoic acid
Liver injury
Apoptosis
