摘要
目的分析济南军区总医院近3年药品不良反应(ADR)发生的规律及特点,制定相应对策,减少或规避ADR伤害、用药风险,保障用药安全。方法对2010年1月—2013年12月上报的ADR(共计465例),按性别、年龄、药品种类、制剂剂型、给药途径、累及器官或组织系统及临床表现等方面进行回顾性分析。结果 465例ADR报告中,静脉滴注给药引发的ADR比例最高,占83.01%;涉及药品种类主要为抗菌药物,占64.51%;ADR累及组织系统-器官及临床表现主要以皮肤、消化系统、循环系统为主,占85.68%。结论重视对医院开展ADR监测工作,加强相关培训,提高医务人员上报意识,为临床提供合理规范用药的理论依据和客观参考,确保用药安全,减少ADR发生。
Objective To analyze the regularity of adverse drug reaction（ADR） in order to take countermeasures,minimize ADR damage,and guarantee the safety of drug use.Methods A total of 465 cases of ADR reported between Jan 2010 and Dec 2013 were retrospectively analyzed,according to gender,age,types of drugs,dosage form,route of administration,organ or tissues involved and specific clinical manifestations.Results Among the 465 cases,intravenous drips caused the largest proportion of ADR,accountiong for 83.01%.The main types of drugs involved were antibacterial drugs that accounted for 64.51%.The main tissues,organs affected and clinical manifestations were the skin,digestive system and circulatory system,accounting for 85.68%.Conclusion Improtance should be attached to surveillance of ADR.Related training should be enhanced and healthcare providers should be made more active to report cases of ADR so as to ensure safe use of drugs.
出处
《解放军药学学报》
CAS
CSCD
2015年第3期274-276,共3页
Pharmaceutical Journal of Chinese People's Liberation Army
关键词
药品不良反应
用药安全
adverse drug reaction
safe use of drugs
