摘要
目的 探讨脑特异性蛋白（S100B）在手足口病（HFMD）合并脑炎患儿脑脊液、血清中的表达与临床应用价值.方法 收治手足口病合并脑炎患儿组30例,单纯手足口病组30例,正常对照组30例,采用酶联免疫吸附试验（ELISA）方法检测患儿脑脊液、血清中S100B水平.结果 手足口病合并脑炎患儿组脑脊液、血清中S100B水平均高于单纯手足口病组和正常对照组,其差异均有统计学意义（P＜0.01）.结论 检测脑脊液、血清中S100B水平对手足口病合并脑炎的早期诊断有一定临床应用价值.
Objective To investigate the expression and its clinic significance of cerebral special protein （S100B） in cerebrospinal fluid （CSF） and serum of hand-foot-mouth disease （HFMD） combined with encephalitis.Methods Enzyme linked immunosorbent assay （ELISA） was used to test S100B in CSF and serum in 30 cases of HFMD combined with encephalitis,30 cases of HFMD,and 30 cases of normal controls.Results The expression level of S100B in CSF and serum of HFMD combined with encephalitis was higher than HFMD and normal controls,with significant difference（P 〈0.01）.Conclusions S100B in CSF and serum has a certain clinical value for early diagnosis of HFMD combined with encephalitis.
出处
《中国医师杂志》
CAS
2015年第7期999-1000,1004,共3页
Journal of Chinese Physician
基金
基金项目：黑龙江省教育厅2013年度科学技术研究（面上）资助项目（12531808）
