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米尔贝肟对犬蠕形螨的临床疗效试验 被引量:3

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摘要 为了研究米尔贝肟对犬蠕形螨的临床疗效,通过对照、平行试验,将15只临床自然感染犬蠕形螨病犬分为5组,每组3只。A组:伊维菌素组(药物对照组):每天单次口服0.5 mg/kg;B至D组为米尔贝肟组(试验组):每天分别单次口服0.5、1.5和2.5 mg/kg(临床推荐剂量的1、3、5倍);E组:犬蠕形螨病组(未用药对照组)。其中,伊维菌素组由0.1 mg/kg开始逐日加到指定剂量并延续。试验持续4个月。结果:米尔贝肟和伊维菌素对犬蠕形螨都有效,临床症状均有缓解。但A组在治疗第3个月出现治愈犬,试验结束时治愈率达67%,B、C和D组在治疗第2个月便有犬治愈,试验结束时B组治愈率为67%,C、D组治愈率100%。在给药期间,犬各项生理指标未见明显变化。本研究为探寻治疗犬蠕形螨提供了更为安全有效的治疗途径,缓解了目前国内治疗犬蠕形螨病药物局限且毒副作用较大的尴尬局面。
出处 《畜牧与兽医》 北大核心 2015年第7期98-101,共4页 Animal Husbandry & Veterinary Medicine
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