摘要
[目的]观察都气加桂汤联合西药治疗阴虚阳郁型慢性心力衰竭疗效。[方法]使用随机平行对照方法,将64例住院及门诊患者按病志号抽签/就诊顺序号方法简单随机分两组。对照组32例抑制神经内分泌ACEI/ARB、β受体阻滞剂、螺内脂(禁忌症除外);利尿剂(呋塞米)减轻心脏负荷;冠心病抗血小板、抗缺血、调脂抗炎;高血压常规降压,房颤患者控制心室率,抗凝;糖尿病控制血糖等。治疗组32例都气加桂汤(中药浓缩颗粒),肉桂12g,茯苓、泽泻、熟地各30g,山萸肉12g,怀山药30g,五味子6g,红景天30g,红花10g,益母草30g;110g/次,2次/d;西药治疗同对照组。连续治疗2周为1疗程。观测临床症状、心功能(NYHA)分级、中医证候积分,血浆NT-pro BNP、6min步行试验、不良反应。连续治疗2疗程,判定疗效。[结果]心功能分级、中医证候积分治疗组优于对照组(P<0.05,P<0.01)。血浆NT-por BNP、6min步行试验均有明显改善(P<0.05,P<0.01),治疗组改善优于对照组(P<0.05,P<0.01)。[结论]都气加桂汤联合西药治疗阴虚阳郁型慢性心力衰竭,疗效满意,无严重不良反应,值得推广。
[Objective] To observe the gas with GUI decoction combined with western medicine treatment curative effect of Yin Yang depression type of chronic heart failure. [Method] Using random parallel control method, 64 cases of inpatient and outpatient patients according to treatment sequence number method is simple and randomly divided into two groups. 32 patients in control group were treated the inhibitory nerve endocrine ACEI/ARB, beta blockers, spironolaetone （contraindications except）; diuretic （furosemide） burden of heart; coronary heart disease of antiplatelet, anti ischemic, lipid anti-inflammatory; conventional blood pressure lowering hypertension patients with atrial fibrillation, ventricular rate control, anticoagulation; diabetes control blood sugar. The treatment group of 32 cases were gas plus GUI Decoction （concentrated granular Chinese traditional medicine）, cinnamon 12g, Poria, Alisma, prepared rhizome of Rehmannia each 30g, Comus officinalis 12g 30g 6G, Chinese yam, Fructus Schisandrae, rhodiola root 30g, safflower 10g, motherwort 30g; 110g/time, 2 times / day. Western medicine treatment with the control group. Continuous treatment for 2 weeks for 1 courses. Observation of clinical symptoms, cardiac function classification （NYHA）, TCM syndrome integral, plasma NT-proBNP, 6min walk test, adverse reaction. Continuous treatment of 2 courses of treatment, curative effect.[Results] Heart function classification, TCM syndrome score in treatment group than in control group （P〈0.05, P 〈0.01）. Plasma NT-porBNP, 6min walk test were obviously improved （P〈0.05, P〈0.01）, the treatment group is better than control group （P〈0.05, P〈0.01）. [Conclusion] Are Qi and yin deficiency and Yang Gui decoction combined with western medicine in the treatment of chronic heart failure type of depression, the curative effect is satisfied, no serious adverse reaction, is worth promoting.
出处
《实用中医内科杂志》
2015年第7期102-104,共3页
Journal of Practical Traditional Chinese Internal Medicine
