摘要
目的:探讨大剂量甲基强的松龙联合丙种球蛋白治疗急性脊髓炎的治疗效果。方法:急性脊髓炎住院患者80例随机分为观察组和对照组,每组40例。观察组给予甲基强的松龙静脉滴注联合丙种球蛋白静脉注射,对照组给予地塞米松磷酸钠静脉滴注联合丙种球蛋白静脉注射。治疗结束后对两组患者的疗效、脊髓功能恢复时间和不良反应等进行比较。结果:观察组的总有效率与临床总获益率均显著优于对照组(P<0.05);观察组患者的退热时间、感觉恢复时间、排尿功能恢复时间、肌力改善两级时间和下床行走时间均显著短于对照组(P<0.05);两组的总不良反应发生率差异无统计学意义(P>0.05)。结论:大剂量甲基强的松龙联合丙种球蛋白治疗急性脊髓炎疗效显著,患者恢复时间短。
Objective： To explore high dose methylprednisolone combined with gamma globulin in the treatment of acute myelitis treatment. Methods： 80 cases of hospitalized patients with acute myelitis were randomly divided into observation group and control group, 40 cases in each group. The observation group was given methylprednisolone intravenous infusion combined with intravenous injection of gamma globulin, the control group was given dexamethasone intravenous infusion combined with intravenous injection of gamma globulin. After the end of treatment, the curative effect of spinal cord function of two groups of patients with recovery time and adverse reaction were compared. Results：The total efficiency of the observation group and the clinical benefit rate was significantly better than the control group, P〈0.05; patients in the observation group the cooling time, recovery time, feeling micturition function recovery time, muscle strength improved two time and ambulation time were significantly shorter than the control group, P〈0.05; tow group in the total adverse reaction rate had no significant difference（P〉0.05）. Conclusion： High dose methylprednisolone combined with gamma globulin is effective in treating patients with acute myelitis, short recovery time.
出处
《中国医药导刊》
2015年第7期707-708,共2页
Chinese Journal of Medicinal Guide
