摘要
目的:了解某院中成药不良反应发生情况及相关因素,为临床安全应用中成药提供参考。方法:使用EXCEL 2003对某医院2010年1月-2012年12月收集的所有中成药不良反应报告,按照其所涉及的患者性别和年龄、给药途径、可疑药物品种及临床表现进行统计分析。结果:药品不良反应发生率与性别关系不显著(男女各占50.00%),41岁以上的患者药品不良反应发生率显著增加,占47.62%;中成药注射剂是发生药品不良反应的主要剂型,占94.04%;所致不良反应的临床表现以皮肤及附件损害为主,高达71.43%。结论:应加强中药注射剂的不良反应监测,提高临床合理用药水平,减少或避免不良反应的重复发生,保证用药安全。
Objective： To offer reference for clinical rational use of Chinese patent medicine by investigating the situation of adverse drug reactions（ADR） and risk factors for the cause of ADR occurred in a hospital.Method： 84 ADR cases were collected from JanuaIy 2010 to December 2012 in a hospital and analyzed statistically by using Microsoft office excel 2003 in respect of patients＇sex, age, routes of administration, variety of drugs and clinical manifestations etc.Result： The incidence of adverse reactions were showed no difference in different genders and it was shown that patients above 41 years old were the high- risk group（47.62%）.The highest incidence occurred in Traditional Chinese medicine injection and the most common manifestation of ADR was lesion of skin and its appendages, which was up to 71.43%.The varieties of Chinese Patent Medicine that caused ADR was chiefly Chinese medicine injection（90.04%）. Conclusion： Great importance should be attached to adverse reactions monitoring of Chinese medicine injection so as to reduce or avoid the occurrence of adverse reactions as well as ensure safe and effective medication.
出处
《中外医学研究》
2015年第21期152-153,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
中成药
药品不良反应
合理用药
Chinese patent medicine
Adverse drug reactions
Rational drug use
