摘要
目的观察玉屏风散颗粒联合转移因子治疗儿童反复上呼吸道感染(RURI)的疗效。方法采用随机分组法将64例入组患儿分成对照组、玉屏风组、转移因子组及联合治疗组,对照组10例,其他3组每组18例;对照组给予常规治疗,其他3组在常规治疗的基础上给予玉屏风散颗粒和/或转移因子胶囊治疗或联合治疗。比较各组患儿治疗期间各种症状、体征持续的时间;酶联免疫吸附试验(ELISA)检测患儿治疗前后血清中Ig A、Ig G及Ig M水平,计数各组不良反应例数。结果转移因子组患儿咳嗽症状持续时间较玉屏风组短;联合治疗组患儿发热、咳嗽及肺内啰音持续时间均较玉屏风组、转移因子组短;转移因子组Ig A水平治疗后较治疗前增加,联合治疗组治疗后Ig A、Ig G及Ig M水平明显高于玉屏风组和转移因子组;对照组不良反应率最高,转移因子组最低,而联合治疗组较玉屏风组低。结论玉屏风联合转移因子治疗儿童反复上呼吸道感染具有可行性。
Objective To evaluate the effect of Yupingfeng powder combined Transfer Factor in treatment of recurrent upper respiratory infection（ RURI） patients. Methods Samples were divided into 4 groups by randomized block method. The four groups were： control group,Yupingfeng Group,Transfer Factor group and combination group. The duration of symptoms and signs in each group was compared. The serum level of Ig A,Ig G and Ig M before or after therapy was analyzed by enzyme linked immunosorbent assay（ ELISA）. The side effect rate was counted. Results During therapy,cough existed shorter in Transfer Factor group than in Yupingfeng group. The continued time of cough,fever and pulmonary rales was the shortest in combination group. The level of Ig A was enhanced after therapy in Transfer Factor group. The serum level of Ig A,Ig G and Ig M was the highest in combination group. The side effect rate in combination group was lower than the control group. Conclusion The combination of Yupingfeng and Transfer Factor in treating recurrent upper respiratory infection is feasible.
出处
《中南医学科学杂志》
CAS
2015年第4期401-403,407,共4页
Medical Science Journal of Central South China
基金
广州市黄埔区科技局(201329-18)
关键词
玉屏风
转移因子
儿童
反复上呼吸道感染
Yupingfeng
Transfer Factor
child
recurrent upper respiratory infection
