摘要
目的:探讨隔日小剂量他达拉非治疗2型糖尿病功能障碍的临床疗效及安全性。方法:110例2型糖尿病功能障碍患者隔日口服他达拉非5mg,共8周。采用国际勃起功能指数问卷(IIEF-5)评分、性生活日记中插入成功率和性交中成功保持勃起至完成性交的成功率、并辅助阴茎勃起硬度等级评定作为治疗前后疗效评价指标。结果:110例患者勃起功能改善者为81例,有效率73.6%;治疗后IIFE-5评分有显著提高;治疗后性生活日记中插入成功率和性交中成功保持勃起至完成性交的成功率明显增高;治疗后阴茎勃起硬度达到Ⅲ级以上有81例;治疗期间无明显不良反应发生。结论:长期隔日小剂量他达拉非可有效治疗2型糖尿病勃起功能障碍,且耐受性良好,可作为临床上一种经济有效的方法。
Objectives： To evaluate the clinical efficacy and safety of tadalafil taken every other day in trea- ting type II diabetes mellitus erectile dysfunction（DMED）. Methods： 110 DMED patients orally took tadalafil of 5 mg every other day for 8 weeks, and were evaluated by international index of erectile function - 5 score （ IIEF - 5 ）, the sexual encounter profile （ SEP 2 and 3） percentage and erectile hardness grading scale （EHGS） before and after the treatment. Results： After treatment, the situation of 81 patients were improved, an effectiveness rate of 73.6% （81/110） ; the scores of IIEF- 5, SEP 2 and 3 percentage and EHGS were significantly improved; and no serious adverse reactions occurred during treatment. Conclusions： Long - term medication of tadalafil every other day is ef- ficacious with good tolerance in the treatment of DMED, which is also economical and worthy promoting clinically.
出处
《中国性科学》
2015年第7期8-10,共3页
Chinese Journal of Human Sexuality
基金
广东省东莞市科技计划重点项目(2011105102020)
关键词
勃起功能障碍
他达拉非
2型糖尿病
小剂量
Erectile dysfunction
Tadalafil
Type H Diabetes mellitus
Small -dose
