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中药止咳汤剂对急性气管炎患者血清中白三烯C4和血小板活化因子的影响

Influence of Cough Decoction of Chinese Herbal Medicine on Leucotriene C4and Platelet Activating Factor in Serum of Patients w ith Acute Bronchitis
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摘要 目的观察中药止咳汤剂对急性气管炎患者血清中白三烯C4和血小板活化因子的影响。方法回顾分析2014年1月—2015年3月接受诊治的60例急性气管炎患者临床资料,根据随机数字表法分别将其分成观察组与对照组,各为30例。其中对照组患者接受常规西药治疗,观察组患者接受中药止咳汤剂治疗,对比两组临床治疗效果。结果两组患者LTc4与PAF水平均有显著下降,其中观察组下降程度更为显著,P<0.01;两组患者在治疗后临床症状均有显著改善,但对比两组积分可得,观察组整体积分低于对照组,P<0.01。结论中药止咳汤剂在临床上治疗急性支气管炎效果显著,可以显著降低血清白三烯C4和血小板活化因子水平,缓解患者临床症状,使用价值大。 Objective To observe the influence of cough decoction of Chinese herbal medicine on leucotriene C4 and platelet activating factor in serum of patients with acute bronchitis. Methods 60 cases of patients with acute bronchitis from January 2014 to March 2015 were retrospectively analyzed and randomly divided into observation group and control group, with 30 cases in each group. Patients in the control group were treated with routine Western medicine, while patients in the observation group were treated with cough decoction of Chinese herbal medicine. The clinical therapeutic effects of the both groups were compared. Results The LTc4 and RAF levels of the both groups dropped significantly, and the observation group dropped more significantly, P〈0.01. After treatment, clinical symptoms of the both groups were improved significantly. Based on comparison of the scores, the overall score of the observation group was lower than that of the control group, P 0.01. Conclusion The clinical effect of cough decoction of Chinese herbal medicine in the treatment of acute bronchitis is significant, can reduce serum leucotriene C4 and the level of platelet activating factor, and relieve clinical symptoms, which has great value.
作者 杜德义
出处 《中国中医药现代远程教育》 2015年第12期47-48,共2页 Chinese Medicine Modern Distance Education of China
关键词 急性气管炎 中药止咳汤剂 白三烯C4 血小板活化因子 咳嗽 acute bronchitis cough decoction of Chinese herbal medicine leucotriene C4 platelet activating factor cough
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