摘要
目的评价急性胰腺炎5种抗菌药物治疗方案成本,探讨急性胰腺炎抗感染治疗的经济有效的治疗方案。方法运用药物经济学分析法、利用PASS合理用药监测系统,对急性胰腺炎非手术治疗中5种抗菌药物拉氧头孢、头孢哌酮他唑巴坦、奥硝唑+头孢他啶、奥硝唑+拉氧头孢、奥硝唑+头孢哌酮他唑巴坦治疗方案进行回顾性分析。结果各组间疗效差异无统计学意义(P>0.05)。奥硝唑+头孢他啶组治疗方案日均抗菌药物成本为(148.84±19.382)元(P<0.05),日均总成本(1 393.5±409.41)元,均较其它各治疗组低(P<0.05)。各组人均住院费用差异无统计学意义(P>0.05)。结论 5组抗菌药物治疗方案疗效相同,奥硝唑+头孢他啶治疗方案成本最低,在药物经济学评价方面具有明显优势。
Objective To evaluate the cost of five kinds of antibiotics medicines in treatment of acute pancreatitis,and find out economical and effective one. Methods The retrospective study methods,and the minimum cost analysis were adopted to perform the pharmaco- economics analysis on five kinds of antibiotics medicines in non- surgical treatment of acute pancreatitis by Prescription Automatic Screening System（ PASS）,which contains Latamoxef,Cefoperazone tazobactam,Ornidazole Ceftazidime,Ornidazole Latamoxef,Ornidazole and Cefoperazone tazobactam. Results The difference of five kinds of antibiotics medicine effective rates was not statistically significant. The average daily cost of antibiotics medicines in Ornidazole Ceftazidime group was（ 148. 84 ± 19. 382） yuan,P〈0. 05）,and the average daily total cost was（ 1 393. 5 ± 409. 41） yuan,which was lower than others. Each group per capita hospital costs was no significant difference. Conclusion Ornidazole Ceftazidime are more economical than others in the average daily cost of antibiotics medicine,and the average daily total cost.
出处
《宁夏医学杂志》
CAS
2015年第7期619-622,共4页
Ningxia Medical Journal
基金
宁夏卫生厅科技资助项目(2012083)
关键词
急性胰腺炎
抗菌药物
最小成本分析
Acute pancreatitis
Antibiotics
Cost-minimization analysis
