摘要
目的:分析我院药品不良反应(ADR)的特点与规律,促进临床合理用药。方法:收集我院2005-2014年网络直报的1 488例ADR报表,利用Excel 2003按年龄、性别、ADR涉及的器官、药品、给药途径等关联性数据分类进行统计分析。结果:我院2005-2014年上报的ADR数量、质量呈逐年上升趋势。1 488例ADR中,男性772例(51.88%),女性716例(48.12%)。10岁以下及60岁以上病例占ADR报告第1,2位,分别为262例(17.61%)和407例(27.35%)。ADR所涉药品品种较多,以抗菌药物和心血管药物及中药注射剂为主,占全部ADR的58.20%。ADR所涉器官以皮肤损害及消化系统占比较大。静脉滴注(962例,64.65%)为主要引发ADR的给药方式。结论:临床越来越重视ADR的搜集和上报工作,应加强给药途径的选择,加强重点人群如婴幼儿及60岁以上老年人的用药监护。
Objective：To analyze the characteristics and regularity of ADRs in our hospital and promote the rational drug use in the clinical practice.Methods：About 1 488 cases of ADR reports in our hospital network from 2005 to 2014 were collected.The relevant data was classified and statistically analyzed by Excel 2003 according to age,gender,ADR involved organs,drugs,and route of drug administration.Results：The quantity and quality of ADR reports from 2005 to 2014 in our hospital increased year by year.Among 1 488 cases of ADR,772 cases（51.88%）were male and 716 cases（48.12%） were female.The most ADR cases occurred in the age groups of under 10 years old（262 cases） and above 60 years old（407 cases） accounting for 17.61% and 27.35%respectively.Among the varieties of drugs involved in ADRs,58.20% ADR cases of the total ADR were caused by antibacterial agents,cardiovascular medicines and Chinese medicine injections.The main clinical manifestations were lesion of skin and digestive system injury.About 962 cases（64.65%） were induced by intravenous administration.Conclusion：More importance has been attached to ADR collection and reporting work in clinical practice,and the selection of appropriate route of drug administration should be strengthened and more pharmaceutical care should be given to the key groups of people such as infants and over 60 years old people.
出处
《中国执业药师》
CAS
2015年第7期49-52,共4页
China Licensed Pharmacist
关键词
药品不良反应
报告
回顾性分析
Adverse Drug Reaction
Report
Retrospective Analysis
