摘要
目的探讨CT／MR-超声造影融合成像在肝癌消融术中即时评价疗效并指导治疗的临床应用价值。方法将计划行消融治疗的肝细胞癌患者随机分为两组，术中分别采用CT／MR-超声造影融合成像和常规超声造影即时评估疗效并指导进一步治疗，术后1个月行增强CT／MR检查判断消融疗效。结果融合成像组共101例患者131个病灶，根据术中评估结果，15．1％的病灶术中即刻进行了补充消融，完全消融率为99．2％；常规超声造影组共93例患者122个病灶，4．2％的病灶进行了补充消融，完全消融率为94．3％，前者补充消融病灶比例及完全消融率均高于后者，差异有统计学意义（P〈0．05）。结论术中CT／MR-超声造影融合成像较常规超声造影能更准确地评估肝癌消融疗效并指导有效再治疗，减少病灶残留，具有重要的临床应用价值。
Objective To evaluate the clinical value of CT/MR-contrast enhanced ultrasound （CEUS） image fusion in immediate assessment for hepatocellular carcinoma（HCC） ablation. Methods Patients diagnosed with HCC to receive ablation therapy were randomly divided into two groups. The ablation for each patient was performed according to their pre-ablation plan. Immediate assessments for the ablation were performed using CT/MR-CEUS image fusion （IF group） and CEUS （CEUS group） separately and whether the need for additional ablations was decided and performed during the therapy. The therapy efficacy was evaluated with enhanced CT or MR 1 month after each complete ablation treatment. Results There were 101 patients with 131 nodules in IF group,and 15.1% of the nodules needed additional ablation according the immediate assessment during the therapy. The complete ablation rate of IF group was 99.2% （125/126）. On the other hand, there were 93 patients with 122 nodules in CEUS group, and 4.2% of the nodules needed additional ablation according the immediate assessment during the therapy. The complete ablation rate of CEUS group was 94.2% （113/120）. IF group has significantly higher additional ablation rate and complete ablation rate than CEUS group （ P 〈0.05）. Conclusions CT/MR-CEUS image fusion can further improve ablation efficacy with accurate intraoperative evaluation and guidance of additional ablation compared with CEUS.
出处
《中华超声影像学杂志》
CSCD
北大核心
2015年第6期508-511,共4页
Chinese Journal of Ultrasonography
基金
国家自然科学基金（基金编号81271699）
关键词
超声检查
融合成像
微气泡
癌
肝细胞
导管消融术
Ultrasonography
Image fusion
Microbubbles
Carcinoma, hepatocellular
Catheter ablation
