摘要
目的：观察银屑病患者发生勃起功能障碍（ED）的一般情况，研究代谢综合征、抑郁、血浆睾酮水平与银屑病患者发生ED的相关性。方法：用国际勃起功能评分表（IIEF-5）对57例银屑病患者及79例正常男性性功能进行评价，并用抑郁自评量表（ CES-D）对参与者抑郁情绪进行评价。同时记录参与者的年龄、身高、体重、血压、血脂、血糖、血清睾酮。结果：IIEF-5评分结果显示57例银屑病患者中30例（52.6％）有ED，79例正常男性中29例（36.7％）有ED。年龄校正的结果显示银屑病组发生ED比例较高，OR值为2.29（95％ CI 1.06～4.98）。单因素分析结果显示银屑病患者年龄、代谢综合征、抑郁症是ED发生的危险因素；多因素分析结果显示抑郁症是ED发生的独立危险因素。结论：银屑病患者ED发生率较高，银屑病患者ED的调查可以作为一项临床常规开展项目。
Objective：To determine the different prevalence of erectile dysfunction （ED） in psoriasis patients in comparison with a healthy control group, and to explore the association of ED with metabolic syndrome, depressive symptoms and hormonal factors in psoriasis.Methods：Fifty-seven psoriasis patients and 79 control men were interviewed by their doctors and completed a questionnaire containing the five-item version of the International Index of Erectile Function （ IIEF-5） and the Center for Epidemiologic Studies Depression Scale （ CES-D） .The information on age, BMI, blood pressure, serum lipid, blood sugar and serum testosterone level were also collected. Results：Thirty of 57 （52.6%） patients with psoriasis recorded an IIEF-5 score indicative of ED, compared with 29 of 79 （36.7%） in control group, reflecting an age-adjusted odds ratio of 2.29 in favour of the psoriasis group （95%CI 1.06-4.98）.A univariate analysis in the psoriasis group indicated that age （ per 5 years） , metabolic syndrome and depressive symptoms were the risk fac-tors for ED.The multivariate logistic regression model indicated that depressive symptoms＆nbsp;was an independent risk factor for ED in psoriasis.Conclusions：The incidence of ED is higher in patients with psoriasis.Screening of ED should become a part of routine care in the management of psoriasis patients.
出处
《皮肤性病诊疗学杂志》
2015年第3期189-192,共4页
Journal of Diagnosis and Therapy on Dermato-venereology
关键词
银屑病
性功能障碍
代谢综合征
抑郁
睾酮
Psoriasis
Erectile dysfunction
Metabolic syndrome
Depression
Testos-terone
