摘要
目的:观察低压无针注射联合硅胶膜治疗瘢痕疙瘩的临床疗效。方法:将198例瘢痕疙瘩患者随机分为三组。对照组:65例,采用普通注射器向瘢痕内注射曲安奈德治疗,每2周1次,连续8次;治疗1组:67例,采用低压无针注射仪向瘢痕内注射曲安奈德治疗;治疗2组:66例,在治疗1组治疗的基础上辅以硅胶膜敷料继续治疗至随访期结束。疗程为16周,随访期为6个月,观察三组患者的有效率、复发率、安全性和治疗中的疼痛程度。结果:对照组有效率49.23%,复发率16.92%,治疗1组有效率为70.15%,复发率为7.46%,治疗2组有效率为72.73%,复发率为1.52%,治疗组有效率明显高于对照组(P<0.05),治疗2组的复发率明显低于对照组(P<0.01);对照组的疼痛评分为6.12±0.27,治疗1、2组分别为3.19±0.23,3.36±0.28,治疗组的疼痛评分明显低于对照组(P<0.01)。结论:低压无针注射联合硅胶膜治疗瘢痕疙瘩疗效好,复发率低,值得临床推广应用。
Objective To observe the clinical efficacy of needle free jet injector and silicone dressing in the treatment of keloid. Methods The selected 198 cases of patients with keloid were divided into three groups randomly.The control group of 65 cases,received intralesional injection of triamcinolone acetonide by ordinary injector once every two weeks for 16 weeks.Treatment group 1 of 67 cases,received intralesional injection of triamcinolone acetonide by needle free jet injector.Treatment group2 of 66 cases were increased by silicone dressing for 6 months.Three groups were observed in the effective rate,recurrence rate,safety and the pain during the treatment. Results The effective rate of control group was 49.23%, the recurrence rate was 16.92.The effective rate of the treatment group 1was 70.15%,the recurrence rate was 7.46%.The effective rate of treatment group 2 was 72.73%,the recurrence rate was 1.52%.The effective rate of the treatment groups were significantly higher than that of the control group（P〈0.05）. The recurrence rate of treatment group 2 was lower than that of control group（P〈0.01）.The pain scores of control group was（6.12±0.27）.The treatment group 1 was（3.19±0.23） and the treatment group 2 was（3.36±0.28）.The pain scores of treatment groups were significantly lower than the control group（P〈0.01）. Conclusion Combined intralesional injection of triamcinolone acetonide by needle free jet injector and silicone dressing is an effective method for treatment of keloid with low recurrence rate,and is worthy of clinical doctors to select.
出处
《中国美容医学》
CAS
2015年第11期56-59,共4页
Chinese Journal of Aesthetic Medicine
关键词
低压无针注射
硅胶膜
瘢痕疙瘩
needle free jet injector
silicone dressing
keloid
