摘要
目的探讨不同类型脑梗死患者睡眠结构的差异及睡眠结构改变与睡眠障碍及抑郁发生的相关性。方法入组258例为收入本院的脑梗死患者,进行睡眠评价及多导睡眠监测,分析不同组别患者各睡眠参数的差异、各睡眠参数与睡眠障碍评分及抑郁评分的相关性、各组患者抑郁的发生率。结果 4组患者睡眠结构的差异均明显(P<0.05),组间比较皮层梗死组及脑干梗死组患者较其他2组患者均不同程度表现出觉醒时间、NREM1+2期延长及NREM3+4期及REM期缩短(P<0.05)。PSQI评分、HAMD评分与微觉醒指数、NREM1+2期呈线性正相关(r>0,P<0.05),与NREM3+4、REM期期呈线性负相关(r<0,P<0.05)。4组患者抑郁的发生率比较无明显差异(P>0.05)。结论皮层下病变更容易出现睡眠结构紊乱,而睡眠结构的改变与睡眠障碍评分及脑梗死后抑郁评分有关,脑梗死后早期患者睡眠结构的改变可能更为明显。
Objective To explore the difference and change of sleep structure among the different types of cerebral infarction and investigate the correlation between sleep structure and depression. Methods 258 pa- tients with cerebral infarction in our hospital was collected. All the patients was evaluated by the sleep scale and monitored by the polysomography. Analyze the difference of sleep parameter among different types of groups and correlation between the score of sleep impairment and depression, compare the incidence rate of de- pression. Results The difference was significant in the sleep structure among the 4 different groups. The a- wake time, NREM 1 ＋ 2 period was longer while the NREM 3 ＋ 4 and REM period was shorter in the group of subcotex and brain stem than the other 2 groups. The score of PSQI and HAMILTON has positive correlation with awake index and NREM 1 ＋ 2 period （r〉0, P〈0. 05）, while there was negative correlation between NREM 3 ＋ 4 and REM period（r〈0,P〈0. 05）. There was no difference in statistics in the incidence of depres- sion. Conclusions Cortical disease is more prone to cause sleep structure disorder, The the score of PSQI and HAMILTON has obviously correlation with sleep structure, the change of sleep structure may be more obvi- ous after stroke.
出处
《卒中与神经疾病》
2015年第3期135-137,共3页
Stroke and Nervous Diseases
关键词
睡眠结构
睡眠障碍
抑郁
Sleep structure
Sleep impairment
Depression
