摘要
目的观察卡介菌多糖核酸联合西替利嗪治疗慢性荨麻疹的疗效及安全性。方法将93例慢性荨麻疹患者随机分为观察组47例和对照组46例,两组均给予西替利嗪口服治疗,观察组在此基础上加用卡介菌多糖核酸注射液肌内注射,均连用8周为1个疗程。观察并比较两组临床疗效和药物不良反应。结果观察组的总有效率显著高于对照组(82.98%VS 60.87%)(P<0.05)。两组不良反应发生率比较,差异无统计学意义(12.77%VS 8.70%)(P>0.05)。结论卡介菌多糖核酸联合西替利嗪治疗慢性荨麻疹疗效肯定,能有效缓解症状,且无明显不良反应。
Objective To observe curative effect and safety of BCG polysaccharide nucleic acid combined with cetirizine in the treatment of chronic urticaria. Methods A total of 93 chronic urticaria patients were randomly divided into observation group with 47 cases and control group with 46 cases. Both groups received cetirizine by oral administration, and the observation group received additional BCG polysaccharide nucleic acid through intramuscular injection. The treatment lasted for 8 weeks as 1 course. Clinical effects and drug adverse reactions were observed and compared in the two groups. Results The observation group had obviously higher total effective rate than the control group （82.98% VS 60.87%） （P〈0.05）. There was no statistically significant difference of incidence of adverse reactions between the two groups （12.77% VS 8.70%） （P〉0.05）. Conclusion Combination of BCG polysaccharide nucleic acid and cetirizine provided precisely curative effect in treating chronic urticaria. This method can effectively relieve symptoms, without obvious adverse reactions.
出处
《中国现代药物应用》
2015年第15期24-25,共2页
Chinese Journal of Modern Drug Application
关键词
慢性荨麻疹
卡介菌多糖核酸
西替利嗪
Chronic urticaria
BCG polysaccharide nucleic acid
Cetirizine
