摘要
目的:观察复律养心汤联合心律平治疗儿童频发室性期前收缩中医辨证为热邪扰心证的临床疗效。方法:将63例中医辨证为热邪扰心证频发室早患儿随机分为试验组(30例)和对照组(33例),分别采用复律养心汤联合心律平,以及单用心律平治疗,共治疗12周。选取临床症状积分、24h室早频数作为观察指标。每4周为1疗程比较各指标改善情况,同时监测用药安全性。结果:与治疗前比较,两组均能减少患儿24h室早频数(P<0.01),试验组在治疗第8周末对室早频数及室早总疗效的改善优于对照组(P<0.05)。治疗第8周末、第12周末试验组总疗效及中医证候疗效改善方面优于对照组(P<0.05)。治疗过程中两组患儿均无明显不良反应发生。结论:复律养心汤联合心律平治疗儿童频发室早热邪扰心证是安全有效的,对患儿临床症状改善优于单纯应用心律平。
Objective： To observe the effect of Fulvyangxin Decoction combined with Propafenone Hydrochloride Tablets on children＇s frequent premature ventricular contractions（FPVCs） with heat-evil offending heart syndrome. Method： 63 patients of FPVCs with heat-evil offending heart syndrome were randomly divided into two groups. Patients in the. Treatment group orally took the traditional Chinese medicine Fulvyangxin decoction and Propafenone Hydrochloride Tablets. Patients in the control group was treated by Propafenone Hydrochloride Tablets alone. During 12 weeks of treatment, the clinical symptoms and frequency of PVCs were observed. The improvement of each index was compared and drug safety was observed. Results： Both clinical symptoms and the results of 24-hour Holter of TC and CG were improved（P〈0.01） after the treatment. For TG, at the end of 8 weeks, the frequency of PVCs, overall efficacy and clinical symptoms were better than that of CG（P〈0.05）.There were no side effects for both TG and CG during the whole course of treatment. Conclusion： The traditional Chinese medicine Fulvyangxin Decoction combined with Propafenone Hydrochloride Tablets could be applied to FPVCs Children with heat-evil offending heart syndrome safely and effectively. Also, the clinical symptoms could be better than Propafenone Hydrochloride Tablets.
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2015年第7期2452-2455,共4页
China Journal of Traditional Chinese Medicine and Pharmacy
关键词
儿童频发室早
热邪扰心证
复律养心汤
室性期前收缩
中医药治疗
心律平
Children＇s frequent premature ventricular contractions
Heat-evil offending heart syndromes
Fulvyangxin Decoction
Ventricular premature contraction
TCM therapy
Propafenone Hydrochboride Tablets
