摘要
受生物膜离子通道结构和功能的启发,人工制备固体纳米孔道门控开关器件一直备受关注.基于仿生纳米孔道的非对称离子传输性质制备的离子二极管和场效应管装置对于构建离子电路和能量转换的纳米器件至关重要.然而,仿生制备的固体纳米孔道在离子传输过程中有漏电流的存在,严重影响了固体纳米孔道应用的灵敏度和信噪比.针对这一问题,研究者利用DNA分子的特殊识别和自组装的功能特性,相继构筑了基于DNA和纳米孔道的智能响应体系.
Inspired by the biological ion channels, DNA supersandwich structures were self-assembled in diamond-shaped mica nanopores, forming highly efficient gate-like nanofluidic switch. Through asymmetric DNA modification in the mica nanopores, rectified ion transport property was observed. The results revealed that DNA, the flexible biological molecules, can also be used to build nanofluidic devices for gating and rectification function in solid-state nanopores with parallel tetrahedron structures.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
2015年第7期1243-1245,共3页
Chemical Journal of Chinese Universities
基金
国家自然科学基金(批准号:11290163,91127025)
国家纳米科技重大专项(批准号:2011CB935700)
北京市科技新星计划项目(批准号:2015B077)资助~~
