摘要
目的:观察社区获得性肺炎患者(CAP)红细胞沉降率、血浆纤维蛋白原、C-反应蛋白水平变化,并探讨其临床意义。方法:选择本院于2012年8月至2014年6月收治的社区获得性肺炎患者70例作为研究对象,作为观察组,同期体检健康人员70例作为对照组,测定并比较治疗前、后两组红细胞沉降率、血浆纤维蛋白原、C-反应蛋白水平差异,并比较观察组重度CAP患者与非重度CAP患者三种检测指标水平差异。结果:70例社区获得性肺炎患者均治愈出院,观察组治疗前ESR、FIB、CRP水平分别为(39.7±9.9)mm/h、(6.9±1.1)g/L、(57.9±17.8)mg/L,均高于对照组,P<0.05。治愈出院时两组比较无明显差异,P>0.05.重度组治疗前ESR、FIB、CRP水平均高于非重度CAP患者,P<0.05,治愈后两组无统计学差异,P>0.05。结论:社区获得性肺炎患者红细胞沉降率、血浆纤维蛋白原、C-反应蛋白水平显著升高,且重度患者其升高愈显著,测定该三类指标有助于诊断及病情评估,具有重要临床价值。
Objective： To observe the changes of erythrocyte sedimentation rate（ ESR）,plasma fibrinogen（ FIB） and C- reactive protein（ CRP） in patients with community acquired pneumonia,and discuss its clinical significance. Methods： 70 cases patients with community acquired pneumonia treated in the hospital in Aug. 2013 to Jun. 2014 were selected as the observation group,70 cases of healthy personsw were acted control group.The level of erythrocyte sedimentation rate,plasma fibrinogen,C- reactive protein were determined and compared before and after treatment in two groups,and compared the difference between severe CAP patients with non severe CAP patients in the observation group,then discussed.Result： 70 cases of community acquired pneumonia patients were cured,ESR,FIB,CRP levels in the observation group were（ 39.7 ± 9.9） mm / h,（ 6.9 ± 1.1） g / L,（ 57.9 ± 17.8） mg / L before treatment,which were higher than those in control group,P〈0. 05. When cured there was no significant difference between the two groups,P〉0. 05.ESR,FIB,CRP levels of severe group before treatment were higher than patients with non severe CAP,P〈0.05,there was no significant difference between two groups when cured,P〉0.05. Conclusion： Erythrocyte sedimentation rate,plasma fibrinogen and C- reactive protein level of pneumonia patients are significantly increased,and in severe patients the rise is more significantly,the determination of the three types of indicators is helpful in the diagnosis and severity assessment,so it has important value.
出处
《河北医学》
CAS
2015年第10期1616-1619,共4页
Hebei Medicine
基金
陕西省医学科技研究基金项目
(编号:2012D24)
关键词
社区获得性肺炎
红细胞沉降率
血浆纤维蛋白原
C-反应蛋白
Community acquired pneumonia
Erythrocyte sedimentation rate
Plasma fibrinogen
C-reactive protein
