摘要
目的：探讨早期干预对极低出生体重早产儿体格及智能发育的影响。方法：选择本院2011年11月至2012年10月新生儿重症监护病房救治存活的极低出生体重早产儿32例做为干预组，选择2011年11月以前出生的9～15个月极低出生体重早产儿连续收录32例做为对照组，对干预组早产儿实施早期干预，定期进行体格发育评价、神经运动检查及智力测验，随访至校正年龄1岁；对照组仅于校正年龄1岁时进行随访。结果：体格发育方面1岁时干预组快于对照组，干预组1岁时智能发育指数（MDI）及运动发育指数（PDI）均明显高于对照组，智力低下及脑瘫发生率低于对照组，差异具有统计学意义。结论：早期干预措施对极低出生体重早产儿体格及智能发育有明显促进作用，能降低早产儿智力低下及脑瘫的发生率，提高其远期生存质量，且以家庭为中心，方法切实可行，基层儿童保健医生应大力宣传推广。
Objective To explore the influence of early intervention on physical and intelligent development of premature infants with very low birth weight. Methods Selected 32 premature infants of very lowbirth weight treated in neonatal intensive care unit during November 2011 to October 2012 as the intervention group. To avoid the violation of medical ethics, we select another 32 premature infants with very low birth weight who were born before November 2011and aged between 9 to 15 months as the control group. The intervention group was treated with early intervention, including regular physical development evaluation, neuromotor examination and test of intelligence. The intervention group was followed-up until correction age of 1 year and the control group was only at the year of correction age of 1 year. Results The physical development in the intervention group was better than the control group at the age of 1, the mental development index （MDI） and psychomotor development index （PDI） significantly higher than those of the control group as well. The incidences of low intelligence and cerebral palsy were lower than those of the control group. The differences were statistically significant. Conclusion Early intervention is obviously effective in promoting the physical and intelligent development of very low birth weight premature infants, reducing the incidence of low intelligence and cerebral palsy, and improving the long-term living quality of the survivors. Still, the method centers on family, and therefore, is feasible and effective. So the doctors for children′s care from basic hospitals should vigorously promote the method.
出处
《实用医学杂志》
CAS
北大核心
2015年第12期1947-1950,共4页
The Journal of Practical Medicine
关键词
脑瘫
早期干预
体格发育
智能发育
早产儿
Cerebral palsy
Early intervention
Physical development
Intelligent development
Premature
