摘要
目的探讨血清前白蛋白与谷丙、谷草转氨酶在新生儿高胆红素血症的临床应用。方法对120例高胆红素血症患儿分别于治疗前、后行血清谷丙转氨酶(ALT),谷草转氨酶(AST)及前白蛋白含量测定。结果 120例患儿治疗前血清ALT、AST、前白蛋白异常率分别为35.00%、40.00%、55.83%,血清前白蛋白与ALT、AST异常率相比较差异均有统计学意义(P均<0.01)。且治疗前后血清前白蛋白的变化与谷丙转氨酶(ALT)、谷草转氨酶(AST)的变化相比差异均有统计学意义(P均<0.01)。结论新生儿高胆红素血症患儿可产生不同程度的肝损伤。血清前白蛋白可作为检测高胆红素血症患儿肝细胞功能的指标。
Objective Study of serum prealbumin and alanine, aspartate aminotransferase in clinical application of neonatal hyperbilirubinemia. Methods The determination on the content of serum alanine aminotransferase （ ALT）, aspartate aminotransferase （AST） and prealbumin from the 120 cases of hyperbilirubinemia were respectively before treatment and after treatment. Results Before the 120 patients treatment, serum ALT, AST, prealbumin abnormal rates were 35% , 40% , 55.83% , serum albumin and ALT, compared with the abnormal rate of AST was obviously different （ all P 〈 0. 01 ）. And with the changes of alanine aminotransferase serum albumin before and after treatment （ALT） , aspartate aminotransferase （AST） were significantly different compared with the change （ P 〈 0. 01 ）. Conclusion Neonatal hyperbilirubinaemia can produce varying degrees of hepatic injury. Serum prealbumin can be used as a testing function of hyperbilirubinemia in liver cell index.
出处
《医药论坛杂志》
2015年第6期76-77,共2页
Journal of Medical Forum
关键词
血清前白蛋白
新生儿高胆红素血症
谷丙转氨酶
谷草转氨酶
Serum prealbumin
Neonatal hyperbilirubinemia
Alanine aminotransferase
Aspartate aminotransferase
