摘要
目的：利用近红外光谱法，建立注射用磷霉素钠含量快速检定方法。方法：采集注射用磷霉素钠的近红外（NIR）光谱，建立近红外定量模型。结果：以矢量归一化和多元散射校正法对光谱进行预处理、选择谱段范围为11995．8—7428．9及6734．6-5454cm^-1。回归方法为偏最小二乘法。结论：该近红外定量分析模型可用于注射用磷霉素钠快速定量分析。
Objective： To develop a near-infrared （NIR） spectrometry method for the rapid determination of fosfomyein sodium for injection. Methods： The quantitative models were established by the collection of NIR spectra of fosfomycin sodium for injection. Results： The spectra were pretreated with the methods of vector normalization and multiple scattering correction, the spectral range of 11 995.8-7 428.9 and 6 734.6-5 454 cm^-1 was chosen, and partial least squares （PLS） was used as the regression method. Conclusion： NIR quantitative analysis model can be used in the rapid quantitative analysis of fosfomycin sodium for injection
出处
《中国药师》
CAS
2015年第7期1241-1243,共3页
China Pharmacist
关键词
注射用磷霉素钠
近红外
定量模型
Fosfomycin sodium for injection
Near-infrared reflectance spectroscopy
Quantitative model
