摘要
急性移植物抗宿主病(aGVHD)是引起异基因造血干细胞移植(allo-HSCT)后,患者非复发性死亡的主要原因之一.目前多数研究聚焦于aGVHD预警指标的研究,以期能够及时控制aGVHD的发生和发展,并获得关于aGVHD病理、生理学的新见解.笔者拟就近年来关于aGVHD预警指标的研究进展进行综述.
Acute graft-versus-host disease (GVHD) is a leading cause of non-relapse mortality following allogeneic hematopoietic stem cell transplantation (allo-HSCT).Alternative approaches to decrease aGVHD-related morbidity and mortality have been focused on the ability to predict aGVHD in an effort to provide an opportunity to abort the development of aGVHD,and to gain new insights into aGVHD pathophysiology.The article reviews recent advances in predicting index of aGVHD.
出处
《国际输血及血液学杂志》
CAS
2015年第3期257-261,共5页
International Journal of Blood Transfusion and Hematology
基金
江苏省临床医学科技专项项目(BL2012022)
关键词
造血干细胞移植
异基因
移植物抗宿主病
急性
预警指标
Hematopoietic stem cell transplantation, allogeneic
Graft vs host disease, acute
Predicting index