摘要
血清甲状腺球蛋白(Tg)水平检测和131I全身扫描(131I-WBS)是分化型甲状腺癌(DTC)随访时判断有无复发与转移的常用指标。多数情况下,DTC患者Tg水平和131I-WBS的结果是一致的。然而,少数患者131I-WBS显示为无功能性甲状腺组织残留,而血清Tg水平增高,131I-WBS不能检测到DTC情况的复发或转移灶。笔者就这类情况的发生以及如何有效监测和治疗患者方面的应用进展进行综述。
Thyroglobulin(Tg)and radioiodine whole body scan(WBS)have been commonly used in follow-up of patients with differentiated thyroid carcinoma(DTC).Tg is associated with radioiodine uptake in local or distant metastases.In minority of patients,the follow-up scan shows no functioning thyroid tissue,but the serum thyroglobulin is still elevated.Therefore,we review recent developments of diagnosis and treatment of those patients with differentiated thyroid cancer and with thyroglobulin elevation but negative iodine scintigraphy.
出处
《生物医学工程学杂志》
EI
CAS
CSCD
北大核心
2015年第3期707-711,共5页
Journal of Biomedical Engineering
基金
四川省教育厅课题资助项目(08zb094)