摘要
目的探讨B型脑钠肽(brain natriuretic peptide,BNP)对急性胰腺炎患者临床治疗及预后的预测价值。方法急性胰腺炎患者66例,根据病情程度分为轻症急性胰腺炎(mild acute pancreatitis,MAP)组36例和重症急性胰腺炎(severe acute pancreatitis,SAP)组30例。于入住SICU后第1天(治疗前)及第5天(治疗后)分别检测患者血浆BNP水平,并比较2组BNP水平。结果治疗前66例急性胰腺炎患者血清BNP[(407.239±71.353)ng/L]高于治疗后[(245.309±64.358)ng/L](P<0.05);SAP组治疗前BNP水平[(445.810±77.864)ng/L]高于MAP组[(375.097±45.760)ng/L)](P<0.05);治疗后2组BNP水平均较治疗前下降(P<0.05),SAP组BNP水平[(291.373±51.848)ng/L]仍高于MAP组[(206.922±46.157)ng/L](P<0.05)。结论动态监测急性胰腺炎患者血浆BNP水平,对评估病情、指导治疗及预后判断有重要意义。
Objective To explore the value of brain natriuretic peptide（BNP）to the assessment of the treatment and prognosis of acute pancreatitis（AP）.Methods Sixty-six patients with AP were divided into mild AP（MAP）group（n=36）and severe AP（SAP）group（n=30）.The serum BNP was detected on the first and fifth days after admission to SICU and the results were compared between two groups.Results The serum BNP level before treatment（（407.239±71.353）ng/L）was significantly higher than that after treatment（（245.309±64.358）ng/L）（p〈0.05）.The serum BNP level was significantly higher in SAP group（（445.810±77.864）ng/L）than that in MAP group（（375.097±45.760）ng/L）before treatment,and higher in SAP group（（291.373±51.848）ng/L）than that in MAP group（（206.922±46.157）ng/L）after treatment（p〈0.05）,significantly lower after treatment than those before treatment in both two groups（p〈0.05）.Conclusion The dynamic detection of serum BNP plays an important role in assessing disease development,guiding treatment and judging prognosis of AP.
出处
《中华实用诊断与治疗杂志》
2015年第6期599-600,共2页
Journal of Chinese Practical Diagnosis and Therapy
关键词
急性胰腺炎
B型脑钠肽
预后
Acute pancreatitis
brain natriuretic peptide
prognosis
