摘要
18F-FDG PET/CT在临床肿瘤诊断中被广泛应用，在鉴别肺良恶性病变中有较大价值。但是18F-FDG并非恶性肿瘤的特异性显像剂，代谢旺盛的炎性细胞（如巨噬细胞、淋巴细胞、嗜酸性粒细胞等）也可表现为18F-FDG高摄取。肺肉芽肿性炎的病理特点主要表现为大量代谢旺盛的炎性细胞浸润，所以肺肉芽肿性炎是导致18F-FDG PET/CT假阳性的主要病变。笔者就肺肉芽肿性炎的PET/CT表现、机制等方面进行综述，以提高PET/CT在肺部肿瘤鉴别诊断中的准确率。
18F-FDG PET/CT has been widely used to diagnose benign and malignant lung tumors. 18F-FDG is not a targeted tumor malignancy indicator because highly metabolic inflammatory cells, such as macrophages, lymphocytes, and eosinophils, also exhibit high 18F-FDG uptake. Granulomatous lung inflammation is pathologically characterized by a large amount of metabolic inflammatory cell infiltration and is therefore the leading cause of false positive 18F-FDG PET/CT uptake. This review aims to improve the accuracy of 18F-FDG PET/CT technique in lung tumor diagnosis and help readers understand PET/CT technique and the mechanism of granulomatous lung inflammation.
出处
《国际放射医学核医学杂志》
2015年第3期264-267,共4页
International Journal of Radiation Medicine and Nuclear Medicine
