摘要
目的:探讨压塑成形口腔矫治器(OA)与CPAP治疗阻塞性睡眠呼吸暂停综合征(OSAS)的临床疗效。方法:收集2012年9月至2014年9月于我院接受治疗的OSAS患者80例,按照随机数字表格法随机分为CPAP组与压塑成形OA组,各40例,分别给予CPAP与压塑成形口腔矫治器治疗,随访6个月,比较两组患者多导睡眠图(PSG)变化及临床症状。结果:治疗后两组患者呼吸暂停平均时间、低通气指数、暂停指数、最低血氧饱和度比较差异具有统计学意义(P均<0.05),组间比较差异无统计学意义(P>0.05)。两组患者治疗期间的舒适度比较差异具有统计学意义(χ2=9.64,P<0.05)。结论:OA与CPAP治疗OSAS的临床疗效相似,建议两种方法交替应用,可有效改善患者病情,值得临床推广及应用。
Objective： To investigate the clinical efficacy of compression molding oral appliance（ OA）and CPAP in treatment of obstructive sleep apnea syndrome（ OSAS）. Method： 80 cases with OSAS were selected from our hospital during the period from Sep. 2012 to Sep. 2014,they were randomly divided into CPAP group and compression molding OA group according to a random number table method,40 cases in each group,they were given CPAP and compression molding oral appliance,followed up for 6 months,polysomnography（ PSG） changes and clinical symptoms of two groups were compared. Result： The average time of apnea,hypopnea index,apnea index,the lowest oxygen saturation after treatment of two groups had statistically significant（ P〈0.05）,there were no statistically significant between two groups（ P〉0.05）. Comfort during treatment of two groups had statistically significant（ χ^2= 9.64,P〈0.05）. Conclusion： OA and CPAP in treatment of OSAS has similar clinical efficacy,recommends the two methods used alternately,can effectively improve the patient＇s condition,worthy of promotion and application in clinical.
出处
《河北医学》
CAS
2015年第8期1388-1390,共3页
Hebei Medicine
基金
陕西省卫生厅科学研究基金项目
(编号:2012B2)
