摘要
目的分析吲达帕胺与双氢克尿噻治疗高血压的临床效果与副作用。方法选择60例原发性高血压患者作为研究对象,将其随机分为对照组和观察组,每组30例。其中对照组患者使用双氢克尿噻进行治疗,观察组患者使用吲达帕胺治疗,比较两组患者治疗前后血压和血生化指标变化情况以及治疗后两组患者血压改善情况和副作用发生情况。结果两组患者治疗后血压均下降(P<0.05);治疗后两组患者血压无显著差异(P>0.05);治疗后观察组患者血钾下降程度高于对照组患者(P<0.05);观察组患者副作用发生率低于对照组患者(P<0.05)。结论吲达帕胺和双氢克尿噻治疗高血压的临床效果均较为显著,而吲达帕胺的副反应少,较为安全。
Objective To evaluate the curative effect of indapamide and dichlothiazide in treating hypertension. Methods To select 60 primary hypertension patients, 30 cases in each group, they were randomly divided into a control group and observation group. The patients of the observation group were treated with indapamide and patients of the control group with dichlothiazide. To survey the right arm blood pressure of the patients with sitting position and blood biochemistry before and within the period of treatment. To note the incidence of adverse reactions of two groups of patients. Results Indapamide and dichlothiazide are all have manifest effect of dropping blood pressure. Compared to dichlothiazide（P〈0.05）, indapamide has less adverse reaction and better tolerance（P〈0.05）. Compared with the observation group and the control group of patients serum potassium decreased significantly after treatment（P〈0.05）. Conclusion Indapamide and dichlothiazide are all have manifest effect of dropping blood pressure, but indapamide has less adverse reaction and side effects.
出处
《中国继续医学教育》
2015年第15期137-138,共2页
China Continuing Medical Education
