摘要
目的通过对不良孕产史夫妇进行外周血染色体核型分析,探讨异常及多态性核型与不良孕产史之间的关系。方法抽取585对不良孕产史夫妇的外周血进行体外培养,常规方法制片,G显带染色体核型分析。结果 1170受检者中检出异常核型28例,检出率2.39%多态性核型58例,占4.96%。结论染色体异常是导致不良孕产史的最主要原因,多态性核型也可导致不良孕产。
Objective： To explore the relationship between negative pregnant history and chromosomal abnormalities and polymorphism by conducted peripheral blood chromosomal karyotyping on couples with negative pregnant history. Methods.. To set up peripheral blood culture among 585 cases of couples, harvested, G-banding and chromosomal karyotyping. Results： 28 cases of abnormalities were detected among 1170 patients with the ratio of 2.39%, 58 cases of polymorphism were detected with the ratio of 4.96%. Conclusion： chromosomal abnormalities were the major reasons to cause negative pregnant history and polymorphism were played an important role as well.
出处
《中国优生与遗传杂志》
2015年第6期42-44,共3页
Chinese Journal of Birth Health & Heredity
基金
深圳市龙岗区科技计划项目(YLWS20140610155602039)
关键词
不良孕产史
染色体核型分析
染色体异常
多态性
Negative pregnant history
Chromosomal karyotyping
Chromosomal abnormalities
Polymorphism
