摘要
目的:探讨ACEI/ARB治疗对高血压伴心房颤动(AF)患者血清hs-CRP的影响及其临床意义。方法:以高血压并AF的85例患者为房颤组,高血压、窦性心律的54例患者为窦律组,按是否接受ACEI/ARB治疗分成窦律非治疗组26例、窦律治疗组28例、房颤非治疗组42例和房颤治疗组43例,比较各组血清hsCRP。结果 :房颤非治疗组血清hs-CRP显著高于窦律非治疗组(P<0.05);窦律组内血清hs-CRP差异无统计学意义(P>0.05);房颤治疗组血清hs-CRP明显低于房颤非治疗组(P<0.05)。结论:高血压伴房颤患者血清hsCRP升高,ACEI/ARB治疗可降低其hs-CRP水平。
Objective：To explore the effect of ACEI/ARB for patients with hypertension complicated with atrial fibrillation （AF） on level of serum hs-CRP and its clinical significance. Methods： 85 patients with hypertension complicated with AF were classified as AF group, 54 patients with hypertension and sinus rhythm （SR） were classified as SR group,and both divided into SR without ACEI/ARB treatment group （n=26）and SR with ACEI/ARB treatment group （n=28）, AF without ACEI/ARB treatment group （n=42） and AF with ACEI/ARB treatment group （n= 43） according to with or without ACEI/ARB therapy. The levels of serum hs-CRP were compared among the three groups. Results： The level of serum hs-CRP in AF without ACEI/ARB treatment group was significantly higher than that in the SR without ACEI/ARB treatment group （P 〈 0.05）,there was no significantly different between with and without ACEI/ARB treatment group （P 〉 0.05）. The level of serum hs-CRP in AF with ACEI/ARB treatment group was significantly lower than that in the AF without ACEI/ARB treatment group （P 〈 0.05 ）. Conclusions： The serum hs-CRP increases in patients with hypertension complicated with AF, and it may reduce after ACEI/ARB treatment.
出处
《岭南急诊医学杂志》
2015年第2期83-84,90,共3页
Lingnan Journal of Emergency Medicine
基金
广东省科技计划项目(2013B021800109)
