摘要
目的:探讨连续血液净化(CBP)对重症脓毒症休克伴心肌损伤患者的影响。方法:将60例重症脓毒症休克并心肌损伤患者随机分为对照组(n=31)和CBP组(n=29),比较两组治疗前及治疗48 h时肌酸激酶同工酶(CK-MB)、脑尿钠肽(BNP)、肌钙蛋白(c Tn I)、动脉血乳酸(LAC)、肺泡动脉氧分压差[P(A-a)O2]、APACHEⅡ评分、心输出量(CO)、平均动脉压(MAP)、心率(HR)及28 d病死率。结果:与对照组相比,CBP组CK-MB、BNP、c Tn I、LAC、P(A-a)O2、APACHEⅡ评分明显降低、MAP升高,心动过速明显纠正,28 d病死率明显降低。结论:血液净化对重症脓毒症休克患者并心肌损伤具有保护作用,可改善患者预后。
Objective：To explore the effect of severe sepstic patients with shock and myocardial damage treated by continuous blood purification （CBP）. Methods： 60 severe septic patients with shock and myocardial damage were randomly divided into control group （n = 31） and CBP group （n = 29）.CK-MB,BNP,cTnI,LAC,P（A-a）O2, APACHE Ⅱ score, CO, MAP, HR and were 28 d mortality were compared between the two groups.Results： Compared with the control group,CK-MB, BNP, cTnI, LAC, P（A-a）O2, APACHE Ⅱ score, HR and the mortality of 28 d significantly decreased （all P 〈 0.05）,while MAP increased in CBP group （P 〈 0.05）. Conclusion：Early CBP treatment can protect severe sepstic patients with shock and myocardial damage and improve the prognosis.
出处
《岭南急诊医学杂志》
2015年第2期81-82,87,共3页
Lingnan Journal of Emergency Medicine
关键词
连续血液净化
脓毒症
休克
心肌损伤
continuous blood purification
sepsis
shock
myocardial damage
