摘要
目的：对浙江省长兴县良性前列腺增生患者下尿路症状的特征进行研究分析。方法：选择2009年3月至2013年9月良性前列腺增生患者2100例作为研究对象,患者年龄介于4781岁之间。将4764岁年龄段患者设为对照组,将6481岁年龄段患者设为观察组,两组各1050例。通过IPSS（国际前列腺症状）评分量表对两组评分,并观察两组患者LUTS（下尿路症状）的严重程度,同时观察LUTS的严重程度和IPSS评分、患者年龄、最大尿流率以及前列腺体积之间的联系,并分析与LUTS严重程度的相关因素。患者均通过口服西药坦索洛新胶囊与中药汤剂进行治疗,疗程结束后观察治疗效果。结果：两组年龄及IPSS评分比较,差异均有统计学意义（P〈0.05）。观察组患者的LUTS中重度比例76.4%大于对照组患者的LUTS中重度比例42.0%,差异均有统计学意义（P〈0.01）。中重度LUTS患者在IPSS评分高、患者年龄、前列腺体积方面均高于轻度LUTS患者,差异均有统计学意义（P〈0.010.05）。中重度LUTS患者最大尿流率低于轻度LUTS患者,差异均有统计学意义（P〈0.01）。患者经过中西结合治疗,IPSS评分显著降低、最大尿流率加快、前列腺体积缩小以及QOL评分降低,差异显著（P〈0.05）。结论：良性前列腺增生患者普遍存在下尿路症状,患者病情的严重程度与年龄、不良习惯存在紧密的联系,因此老年良性前列腺增生患者需要养成良好的生活习惯防止疾病的恶化。患者经中西医结合治疗后症状得到显著改善、生活质量得到明显的提高。
Objectives： To analyze the characteristics of lower urinary tract symptoms in patients with be-nign prostatic hyperplasia in Changxing county of Zhejiang province. Methods： 2100 patients with benign prostatic hyperplasia from March 2009 to September 2013 were selected and the age of them ranged from 47 - 81 years old. Patients between 47 and 64 years old were control group, and the 64 -81 years old group was the observation group with 1050 cases in each group. The IPSS Rating Scale score of two groups were observed as well as the relationship among the severity of LUTS and LUTS, patients age, IPSS score, maximum urinary flow rate and volume of the prostate. The related factors of the severity of LUTS were analyzed. Patients were all treated by oral administration of western medicine tamsulosin capsules and the decoction of Chinese medicine to observe the therapeutic effect after the treatment. Results： With respect to Age and IPSS scores, the difference between two groups was statistically significant （P 〈 0. 05）. Moderate and severe rate of LUTS in observation group and control group was 76.4% and 42% respectively, with statistically significant difference （ P 〈 0. 01 ）. The high IPSS score, patient age and pros- tate volume of moderate and severe LUTS patients were better than these of mild LUTS patients, with statistically significant difference （P 〈 0.01 -0. 05 ）. The maximal urinary flow rate of moderate and severe LUTS patients was lower than that of mild LUTS patients, with statistically significant difference （P 〈 0. 01 ）. In patients treated with integrated traditional Chinese and western medicine treatment, the IPSS score decreased significantly; the maximal urinary flow rate accelerated; prostate volume and QOL score decreased significantly （P 〈 0. 05）. Conclusion： Lower urinary tract symptoms are prevalent in patients with benign prostatic hyperplasia. There is a close relationship between the severity of the disease and patient＇s age and bad habits. Therefore,
出处
《中国性科学》
2015年第6期16-19,共4页
Chinese Journal of Human Sexuality
基金
浙江省湖州市科技计划项目(2012YSB25)
关键词
长兴县
良性前列腺增生
下尿路症状
特征分析
坦索洛新胶囊
中药
Changxing county
Benign prostatic hyperplasia
Lower urinary tract symptoms
Fea-ture analysis
Tamsulosin capsules
Traditional Chinese medicine
