期刊文献+

右美托咪定在困难气道患者的应用

Appliation of Dexmedetomidine in Difficult Airway Patients
下载PDF
导出
摘要 目的探讨右美托咪定在困难气道患者麻醉诱导中的效果。方法回顾性分析困难气道患者60例,根据麻醉情况分为右美托咪定组、咪达唑仑组和异丙酚组,比较3组患者麻醉诱导过程中呼吸抑制、气道阻塞以及血压、心率、血氧饱和度的变化。结果右美托咪定组的呼吸抑制、气道阻塞明显低于其他两组(P<0.05),血压、心率、血氧饱和度的波动也明显少于其他两组(P<0.05)。结论右美托咪定应用于困难气道患者的麻醉诱导可以显著降低呼吸抑制、气道阻塞的发生率,维持患者在诱导过程中血压、心率、血氧饱和度的平稳。 Objective To analyze the clinical effects and the values about application of the dexmedetomidine in dif- ficult airway patients during anesthesia induction. Methods 60 difficult airway patients were divided into group of dexmedetomidine (20 patients ) ,group of midazolam (20 patients ) and group of propofol(20 patients ) in the second Af- filiated Hospital from July 2011 to October 2013. We observed their respiratory depression, airway obstruction and the chan- ges of blood pressure (BP) ,heart rate (HR), and blood oxygen saturation (BOS) during anesthesia induction. Results The rate of respiratory depression and airway obstruction is obviously less than medazolam group and propofol group. The changes of BP, HR, and blood oxygen saturation are less than the other groups. ( P 〈 0.05 ). Conclusion Appling dexmedetomidine can obviously decrease the rate of respiratory depression and airway obstruction. It can also maintain BP, HR and blood oxygen saturation during anesthesia induction.
作者 王燕 曾高峰
出处 《中南医学科学杂志》 CAS 2015年第3期308-310,共3页 Medical Science Journal of Central South China
关键词 右美托咪定 困难气道 麻醉诱导 呼吸抑制 气道梗塞 心血管反应 dexmedetomidine difficult airway anesthesia induction respiratory depression airway obstruc-tion(awo) cardiovascular response
  • 相关文献

参考文献9

  • 1于布为,吴新民,左明章,邓晓明,高学,田鸣.困难气道管理指南[J].临床麻醉学杂志,2013,29(1):93-98. 被引量:226
  • 2Murrell JC,Hellebrekers LJ.Medetomidine and dexmedetomidine:a review of cardiovascular effects and antinociceptive properties in the dog[J].vet Anaesth Analg,2005,32(3):117-127. 被引量:1
  • 3Kwak HJ,Min SK,Yoo JY,et al.The median effective dose of dexmedetomidine for laryngeal mask airway insertion with propofol 2.0 mg/kg[J].Acta Anaesthesiol Scand,2014,58(7):815-819. 被引量:1
  • 4Savla JR,Ghai B,Bansal D,et al.Effect of intranasal dexmedetomidine or oral midazolam premedication on sevoflurane EC50 for successful laryngeal mask airway placement in children:a randomized,double-blind,placebo-controlled trial[J].Paediatr Anaesth,2014,24(4):433-439. 被引量:1
  • 5Koruk S,Mizrak A,Kaya Ugur B,et al.Propofol/dexmedetomidine and propofol/ketamine combinations for anesthesia in pediatric patients undergoing transcatheter atrial septal defect closure:a prospective randomized study[J].Clin Ther,2010,32(4):701-709. 被引量:1
  • 6Nelson LE,Lu J,Guo T,et al.The alpha2-adrenoceptor agonist dexmedetomidine converges on an endogenous sleep-promoting pathway to exert it’s sedative effects[J].Anesthesiology,2003,98(2):428-436. 被引量:1
  • 7Venn RM,Hell J,Grounds RM.Respiratory effects of dexmedetomitine in the surgical requiring intensive care[J].Crit care,2000,4(5):302-308. 被引量:1
  • 8Wijeysundera DN,Naik JS,Beattie WS.Alpha-2 adrenergic agonists to prevent perioperative cardiovascular complications:ameta-analysis[J].Am J Med,2003,114(9):742-752. 被引量:1
  • 9Biccard BM,Goqa S,de Beurs J.Dexmedetomidine and caediac protection for non-cardiac surgery:a meta-analysis of randomized controlled trials[J].Anaesthesia,2008,63(1):4-14. 被引量:1

二级参考文献1

共引文献225

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部