摘要
天麻素是中药天麻中的主要活性成分之一,由于药理作用广泛,毒副作用小,受到人们的广泛关注。近年来,国内外多项研究证明,天麻素可以减轻脑缺血再灌注损伤、改善帕金森病与老年性痴呆症病情、抑制神经性疼痛,还能对其他神经系统疾病起到一定的防治作用。因此,本文对天麻素在神经系统的药理作用及作用机制做了详细阐述,并对其开发、利用提供思路和理论依据。
Gastrodin is a main active constituent of Tianma, which is paid close attention because of extensive pharmacologi cal effects and little toxic effects. In recent years, the role played by gastrodin was shown by several studies. The effects in cluded reducing cerebral ischemia-reperfusion injury, improving Parkinson＇s disease and senile dementia disease, inhibiting neu ropathic pain and effects in other neurological disorders. Therefore, its pharmacological effects and mechanism in nervous sys tern were elaborated in this article to provide thread and theoretical basis for exploitation and utilization.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
2015年第11期1047-1050,共4页
Chinese Journal of Hospital Pharmacy
关键词
天麻素
脑缺血再灌注
帕金森病
老年性痴呆
神经性疼痛
gastrodin brain ischemia reperfusion Parkinson disease
senile dementia
neuropathic pain
