摘要
目的探讨四维CT的放疗技术在肺癌三维调强放射治疗中的应用效果。方法回顾性分析我院42例肺癌患者应用四维CT的放疗技术治疗的临床资料。结果 42例患者均获得随访,其中完全缓解6例,部分缓解27例,无好转8例,进展1例,总有效率为78.57%。其中急性放射性肺损伤1级34例(80.95%),2级7例(16.67%),3级1例(2.38%),急性放射性食管炎1级34例(80.95%),2级3例(7.14%)。4D计划CTV高于3D计划,PTV小于3D计划,肺V20、MLD低于3D计划,差异有统计学意义(P<0.05)。结论四维CT应用于肺癌三维调强放射治疗中可行、有效,能够减少计划靶区的体积,提高放射治疗疗效。
Objective：To investigate the efficacy of four-dimensional CT for the three-dimensional intensity modulated radiotherapy of patients with lung cancer.Methods A retrospective analysis of clinical data of 38 cases of lung cancer patients in the four-dimen-sional CT radiotherapy treatment.Results The total efficiency was 78.57%,the displacement of lung tumor respiratory motion was differ-ent in three dimensions, especially in the Vertical direction about（9.0 ±2.2） mm, Accuracy of the distance was2.5mm,the plan-4Ds CTV was bigger than Plan-3D,but its PTV was less than the Plan-3D significantly, at the same time its lung V20,MLD were both less than the Plan-3D,and the difference was statistically significant（P〈0.05）.Conclusion Through applications to four-dimensional CT is feasible, effective, and can reduce the volume of the planning target volume, and help to improve the accuracy of radiotherapy.
出处
《黑龙江医学》
2015年第5期541-542,共2页
Heilongjiang Medical Journal
关键词
肺癌
四维CT
放射治疗
Lung cancer
Four - dimensional CT
Radiotherapy
