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同步推量调强放疗治疗多发脑转移瘤的疗效分析 被引量:4

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摘要 目的了解同步推量调强放疗治疗多发脑转移瘤近期临床疗效和毒性反应。方法 43例多发脑转移患者随机分为同步推量调强放疗组(调强组22例)与序贯推量适形组(适形组2 1例)。调强放疗组:全脑放射剂量45Gy,1.8Gy/次;转移病灶55Gy,2.2Gy/次,5次/周,共25次。适形组:全脑放疗剂量40Gy,2Gy/次,5次/周,共20次;局部缩野总剂量50-60Gy,2Gy/次,5次/周,共5-10次。结果调强放疗组和适形放疗组近期有效率(CR)分别为90.9%和6 1.9%,具有显著性差异(P〈0.05)。调强组和适形组1年生存率分别为分别为59%和42%。不良反应发生率调强组和对照组,无显著性差异(P=0.846)。结论同步推量调强放疗治疗多发脑转移瘤是一种更有效的放疗手段,值得临床推广。
出处 《中国农村卫生》 2015年第6期54-55,共2页
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