摘要
目的探讨胆碱能杀虫剂中毒后发生中间综合征(IMS)的相关危险因素。方法收集324例患者的一般临床资料包括年龄、性别、基础疾病,以及毒物类型、中毒途径、治疗方法、IMS的临床特征。观察IMS的发病率,并分析其相关危险因素。结果 16.4%患者发生IMS,死亡率39.6%,其中男性占66.7%,且年龄>45岁是IMS进展的显著危险因素[RR 2.67,95%CI(1.31,4.72),P<0.05],而多次洗胃则是保护因素[RR 0.35,95%CI(0.11,0.79),P<0.05]。结论 IMS的发生与年龄>45岁、洗胃次数多少相关,而与洗胃时机和毒物类型无关。
Objective To investigate related risk factors of intermediate syndrome （IMS） after cholinergic pesticides poisoning.Methods Collections were made on clinical data of age, gender, underlying disease, poison type, poisoning route, treatment method, and clinical characteristics of IMS in 324 cases. Morbidity of IMS was observed to analyze its related risk factors.Results There were 16.4% of the patients had IMS with the mortality rate as 39.6%, and 66.7% of them was male patients. Aging 〉45 years old was a significant risk factor of IMS [（RR 2.67, 95%CI（1.31, 4.72）,P〈0.05）], while repeated gastric lavage is the protective factor [（RR 0.35, 95%CI（0.11, 0.79）,P〈0.05）].Conclusion There is a correlation in IMS, age 〉45 years old and gastric lavage times, while IMS is not related with time of gastric lavage and poison type.
出处
《中国实用医药》
2015年第13期26-27,共2页
China Practical Medicine
关键词
中毒
中间综合征
危险因素
Poisoning
Intermediate syndrome
Risk factors
