摘要
目的:研究黄麦颗粒的制备工艺,确定最佳工艺条件。方法:采用单因素筛选法和正交设计法,进行提取工艺和成型工艺优选。结果:最佳工艺为处方量的7味药材,加8倍量水,煎煮2 h,提取3次,合并水提液,减压浓缩、干燥成干浸膏。干膏粉与适量糊精混合均匀后,加40%乙醇湿法制粒,干燥后整粒,即得。结论:所选工艺科学、合理、稳定,适合工业化生产。
Objective： To determine the optimal preparation conditions for Huangmai granules. Methods： Using single factor screening method and orthogonal design method, the extraction process and granulation process were optimized. Results： The optimal preparation process was as follows ： the medicinal materials in the prescription were extracted 3 times with 8-fold amount of water with 2h for each time. The water extract was combined followed by vacuum concentration, and then dried to obtain dry. extract. The powder of dry extract was evenly mixed with dextrin at appropriate amount, and the wet granules were prepared with the 40% ethanol followed by drying and size stabilization to obtain the products. Conclusion： The selected preparation process is scientific, reasonable and sta- ble, and suitable for the industrial production.
出处
《中国药师》
CAS
2015年第6期901-904,共4页
China Pharmacist
基金
上海市科学技术委员会科技支撑项目(编号:12401900502)
关键词
黄麦颗粒
制备工艺
淫羊藿苷
二苯乙烯苷
Huangmai granules
Preparation process
Icariin
Stilbene glucoside
