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影响前列腺增生合并膀胱过度活动综合征患者术后效果的多因素回归分析 被引量:23

Multi-factor analysis of factors influencing the outcomes in patients with benign prostatic hyperplasia and overactive bladder after transurethral resection of the prostate
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摘要 目的 探讨影响前列腺增生(BPH)合并膀胱过度活动综合征(OAB)患者行前列腺电切术(TURP)后效果的恢复因素.方法 分析我院收治216例BPH合并OAB行经尿道前列腺电切术患者的临床资料,统计患者的年龄、血压、血糖、前列腺体积、残余尿量、平均尿流率、最大尿流率、逼尿肌稳定性、国际前列腺症状评分(I-PSS)、泌尿系感染、尿潴留等资料收集,先对相关数据进行单因素分析,再进行Logistic回归分析.结果 单因素分析表明,残余尿量(x2=4.761,P<0.05)、I-PSS(x2=9.313,P<0.05)、最大尿流率(x2=4.539,P<0.05)、逼尿肌稳定性(x2=5.252,P<0.05)是影响患者预后的重要因素;多因素分析表明,I-PSS[比值比(OR)=1.952,P<0.05]和逼尿肌稳定性(OR =2.791,P<0.05)是其独立危险因素.结论 I-PSS及逼尿肌稳定性是影响BPH合并OAB患者TURP术后效果恢复的独立危险因素. Objective To study the factors influencing the factors influencing the prognosis in patients with benign prostatic hyperplasia (BPH) and overactive bladder (OAB) subject to the transurethral resection of the prostate (TURP).Methods A total of 216 patients diagnosed with BPH and OAB in our hospital were treated with TURP.Clinical data including age,blood pressure,blood glucose,prostate volume,residual urine volume,average urinary flow rate,maximum urinary flow rate,detrusor instability,international prostate symptom score (I-PSS),urinary infection,urinary retention and other aspects were collected in our study.The related data were used for univariate analysis first.Multivariate analysis was done by the Logistic regression.Results Univariate analysis showed that the following features were associated with the prognosis of patients with TURP:residual urine volume (x2 =4.761,P < 0.05),I-PSS (x2 =9.313,P <0.05),maximum urinary flow rate (x2 =4.539,P <0.05) and detrusor instability (x2 =5.252,P <0.05).Multivariate analysis showed that the following features were independently associated with prognosis of patients subject to TURP:I-PSS and detrusor instability.Conclusion I-PSS [odds ratio (OR) =1.952,P < 0.05] and detrusor instability (OR =2.791,P < 0.05) could be independent predictive factors in the clinical efficacy of TURP in the patients with BPH and OAB.
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2015年第6期1303-1305,共3页 Chinese Journal of Experimental Surgery
关键词 前列腺增生 膀胱过度活动综合征 国际前列腺症状评分 危险因素 Benign prostatic hyperplasia Overactive bladder International prostate symptom score Risk factors
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