摘要
目的：构建中药水提液在反渗透膜处理过程中渗透压与电导率的相关性方程模型。方法：通过对黄芩、栀子、六味地黄丸等25个单、复方中药水提液体系在反渗透膜过程中渗透压（π）与电导率（e）的相关性分析,以药液质量浓度为桥梁,提出渗透压-电导率相关性模型,选择栀子、六味地黄丸水提液加以验证。结果：中药水提液e在0.78~7.26 ms·cm^-1时,与其相应的渗透压具有良好的线性关系（R2=0.964 2）;栀子水提液渗透压与电导率在反渗透膜过程中具有相似的变化规律,且二者均与药液质量浓度呈正相关。栀子水提液在25~250 g·L^-1时符合方程π=0.088 0e-0.050 1,六味地黄丸水提液在25~125 g·L^-1时符合方程π=0.368 4e-0.118 9,计算值与实测值均无显著性差异。结论：构建的中药水提液渗透压与电导率的相关性模型具有一定的适应性,为中药反渗透膜过程实现渗透压在线检测提供简单、有效、可靠的手段。
Objective： To investigate relationship between osmosis pressure and conductivity of Chinese medicine decotion, and construct model of them. Method： This model was based on the concentration of decotion, which had a postive effect on osmosis pressure and conductivity in some degree. There were 25 system to research relationship between osmosis pressure and conductivity. Rationality of the model was verified by taking Gardeniae Fructus decotion and Liuwei Dihuang Wan decotion as experimental subjects. Result： They had good linear relation in the range of 0.78-7.26 ms·cm^-1of conductivity, the correlation coefficient was 0. 964 2. As time went on, the change rule of osmosis pressure and conductivity was similar, in addition, they both had positive relationship with decotion concentration. Fitting equations of Gardeniae Frnctus decotion （25-250 g·L^-1 ） and Liuwei Dihuang Wan decotion （25-125 g·L^-1） were 7r =0. 088 0e -0. 050 1 and ~r =0. 368 4e -0. 118 9. These calculated values and measured values were no significant difference. Conclusion： The model of osmosis pressure and conductivity building in this study is proved to be efficient in some degree. It provides a simple, efficient and reliable way to detect osmosis pressure on line in reverse osmosis membrane of Chinese medicine decotion.
出处
《中国实验方剂学杂志》
CAS
CSCD
北大核心
2015年第12期1-4,共4页
Chinese Journal of Experimental Traditional Medical Formulae
基金
国家自然科学基金项目(81274096)
江苏省科技厅自然科学基金项目(BK 2012855)
江苏省科技厅产学研联合创新项目(BY 2012036)
江苏省高校优势学科建设工程项目
关键词
渗透压
电导率
相关性模型
栀子
六味地黄丸
水提液
osmosis pressure
conductivity
relativity model
Gardeniae Fructus
Liuwei Dihuang Wan
water extract
