摘要
目的探讨血中肌钙蛋白I(c Tn I)、肌钙蛋白T(c Tn T)、N端前B型脑钠肽(NT-pro BNP)联合检测在急性心肌梗死(acute myocardial infarction,AMI)诊断中的应用价值。方法选取急性胸闷胸痛为主要症状的患者34例,以2010年AMI临床诊断与治疗指南将受试者分为AMI组(n=20)和非AMI组(n=14)。就诊时即抽取血样,用电化学发光法法测定入组者血浆中的c Tn I、c Tn T、NT-pro BNP的浓度。结果 AMI患者NT-pro BNP浓度均值为3580.40 pg/m L,非AMI组为167.6 pg/m L,NT-pro BNP浓度较对照组明显升高,差异有统计学意义(P<0.05);c Tn I、c Tn T浓度较非AMI组亦明显升高,差异有统计学意义(P<0.05)。结论 NT-pro BNP、c Tn I、c Tn T联合检测可以使AMI检测的敏感性升高,有助于AMI的早期诊断。
Objective Investigate the value of serum Cardiac troponin I, cardiac troponin T and NT-proBNP combined detection in acute myocardial infarction diagnose.Methods Collected 34 patients who have the with acute chest pain as the main symptom treatment for the study, the blood samples were drawn when the patients in the treatment, all the samples use electricity chemiluminescence method to detect the plasma cTnI, cTnT, NT-proBNP concentrations.Results NT-proBNP concentration in patients with AMI mean is 3580.40 pg/mL, the control group was 167.6 pg/mL, compared with the control group was significantly higher in patients with NT-proBNP, the difference was statistically significant （P〈0.05）;plasma cTnI、cTnT compared with the control group also significantly increased, the difference was statistically significant（P〈0.05）.Conclusion NT-proBNP, cTnI, cTnT combined detection of AMI detection sensitivity can be improved to help early diagnosis of AMI.
出处
《当代医学》
2015年第17期42-43,共2页
Contemporary Medicine
