摘要
目的观察马来酸氟吡汀治疗腰椎间盘突出症疼痛的临床疗效和安全性。方法选取符合腰椎间盘突出症疼痛患者80例,随机均分为观察组(口服马来酸氟吡汀胶囊)和对照组(口服洛芬待因缓释片),对比两组的临床疗效和不良反应发生情况。结果观察组治疗后疼痛视觉模拟评分法(VAS)评分显著低于对照组(P<0.05);观察组临床总有效率为100.00%,高于对照组的95.00%,但差异无统计学意义(P<0.05);观察组的不良反应轻微,与对照组比较,差异无统计学意义(P>0.05)。结论马来酸氟吡汀治疗腰椎间盘突出症疼痛有较好的临床疗效,且安全性高,可临床推广。
Objective To research the clinical efficacy and safety of flupirtine maleate for treating pain of intervertebral disc protrusion. Methods 80 cases of pain of intervertebral disc protrusion conformed to the inclusion criteria were selected and divided into the observation group and the control group randomly. The observation group was given oral flupirtine maleate and the control group was given oral Ibuprofen Codeine Sustained Release Tablets. The clinical effects and adverse reactions were compared between the two groups. Results The visual analogue scale （VAS） score after treatment in the observation group was distinctly lower than that in control group （P 〈 0.05）; while the clinical efficacy was higher than that in the control group（100.00% vs. 95.00% ）, the differences were statistical significant（ P 〈 0.05）. The adverse reactions in the observation group were mild, had no statistical difference compared with the control group（ P 〉 0.05）. Conclusion Flupirtine maleate has better effect and high safety for the treatment of pain of intervertebral disc protrusion.
出处
《中国药业》
CAS
2015年第11期94-95,共2页
China Pharmaceuticals
基金
广西壮族自治区卫生厅科研科题
项目编号:Z2013286
关键词
腰椎间盘突出症
疼痛
马来酸氟吡汀
intervertebral disc protrusion
pain
flupirtine maleate
