摘要
目的 探讨扩张器包膜对自体异位移植后兔肋软骨生物力学性能的影响.方法 在10只3月龄新西兰大白兔背部脊柱两侧对称埋置15 ml扩张器各4枚,持续扩张1个月后,取出扩张器,一侧去除扩张器包膜为去包膜组,一侧保留扩张器包膜为带包膜组,同时取右侧第7、8肋软骨,去除肋软骨膜后一分为二,分别放置于背部对称扩张囊腔内,分别于术后4、8周取左右对称部位的肋软骨,进行组织学观察.根据试验机要求制成相应大小标准试件进行生物力学测试,对测试结果进行统计学分析处理.结果 8周后,平均极限抗拉强度：去包膜组为（4.954＋2.8） MPa,带包膜组为（2.939＋0.842） MPa;平均压缩强度：去包膜组为（58.74±13.77） MPa,带包膜组为（47.61±11.41） MPa,去包膜组的抗拉强度及压缩强度均高于带包膜组,差异均有统计学意义（P＜0.05）,表明去包膜组肋软骨各项生物力学性能优于带包膜组.结论 去除扩张器包膜对移植后肋软骨生物力学性能的保持优于保留扩张器包膜组.
Objective To explore the effect of the expanded capsule on biomechanics of the transplanted autologous costal cartilage.Methods Ten New Zealand white rabbits aged 3 months were involved and four 15 ml tissue expanders were implanted symmetrically on the back of each rabbit.After 1 month,expanded capsules were removed （experimental group） on the left side and were reserved （control group） on the right side.Meanwhile,the 6th and 7th costal cartilage without the perichondrium were taken out and each cartilage was divided into two pieces and put under the expanded capsule symmetrically.The cartilage at the upper sides and lower sides were taken out at 4 weeks and 8 weeks later,respectively.All the cartilages were sculptured for the demand of the machine text.The tension and compression property of the cartilages were assessed by the material testing machine（Instron 5967） and the results were analyzed statistically.Results 8 weeks lateral,the average ultimate tension strength was （4.954 ＋ 2.8） MPa in experimental group and （2.939 ＋ 0.842） MPa in control group.The average compressive strength was （58.74 ± 13.77） MPa in experimental group,and（47.61 ± 11.41） MPa in control group.The biomechanics property of the cartilages in the experimental group is better than the control group,and the differences were statistically significant.Conclusions Removing the expanded capsule is benefical to maintain the biomechanics of autologous costal cartilage.
出处
《中华整形外科杂志》
CAS
CSCD
北大核心
2015年第3期205-208,共4页
Chinese Journal of Plastic Surgery
基金
2010卫生部临床学科重点项目
首都卫生发展科研项目（2011-4004-01）
关键词
肋软骨
移植
自体
扩张包膜
生物力学
Costal cartilage
Transplantation, autologous
Expanded capsule
Biomechanics
