摘要
目的:探讨持续血液净化(CRRT)治疗利尿剂抵抗急性失代偿性心力衰竭(ADHF)的临床疗效。方法:选取2012年1月30日-2014年6月30日本院收治的58例利尿剂抵抗急性失代偿性心力衰竭患者为研究对象,按治疗方法及治疗时机不同,分为对照组26例,采用其他常规心衰治疗,早期CRRT治疗组17例,常规CRRT治疗组15例,对比三组的治疗效果。结果:三组患者治疗后48 h呼吸频率、心率、血压、血氧饱和度等临床指标及肌酐下降幅度、尿量增加幅度、脑钠肽下降幅度比较差异均有统计学意义(P<0.05)。结论:采用持续血液净化治疗利尿剂抵抗急性失代偿性心力衰竭,可使患者临床指标维持在正常范围,加大肌酐下降幅度、尿量增加幅度及脑钠肽下降幅度,促进治疗效果,且早期进行持续血液净化治疗的效果更加明显,值得临床广泛应用。
Objective：To study and explore the clinical efficacy of continuous renal replacement treatment （CRRT） on acute decompensated heart failure （ADHF） of diuretic resistance.Method：Fifty patients with acute decompensated heart failure of diuretic resistance who were admitted by the hospital from January 30 2012 to June 30 2014 were selected as research subjects,they were divided into the control group （26 cases,other conventional treatment of heart failure）,early CRRT treatment group （17 cases） and conventional CRRT treatment group （13 cases）according to different treatment methods and treatment opportunities,the treatment efficacies of patients in the three groups were compared.Result：The differences in mutual comparisons in the breathing rate,heart rate,blood pressure,blood oxygen saturation,creatinine drop,increase scope of urine and falling range of brain natriuretic peptide were statistically significant（P〈0.05）.Conclusion：ADHF applied on acute decompensated heart failure with diuretic resistance can maintain clinical indexes of patients within normal range,accelerate the decrease of creatinine,the increase of urine volume and the decrease of brain natriuretic peptide,which can promote therapeutic effects.The effect of early CRRT is more obvious,being worthy of wide application in clinical practices.
出处
《中国医学创新》
CAS
2015年第17期41-43,共3页
Medical Innovation of China
关键词
持续血液净化治疗
利尿剂抵抗
急性失代偿性心力衰竭
效果
Continuous renal replacement treatment
Diuretic resistance
Acute decompensated heart failure
Effect
