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不同年龄小阴茎儿童的内分泌治疗 被引量:4

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摘要 目的探讨激素治疗不同年龄小阴茎儿童的性腺反应和阴茎生长效果。方法纳入18岁以下单纯小阴茎患儿共25例,分为〈11岁组(青春前期)和≥11岁组(青春/青春后期)。≥11岁组予促绒毛膜性腺激素1 500~2 000 U肌肉注射,1次/周,6周为一疗程。〈11岁组予肌肉注射庚酸睾酮素25 mg/次,1次/月,3个月为一疗程。两组患儿均予测量激素治疗前后阴茎伸直长度及睾丸容积,治疗一疗程后予查血清睾酮素。结果治疗后,两组的阴茎长度及睾丸容积均有所增加,差异有统计学意义(P〈0.01)。≥11岁组治疗前血清睾酮基础水平〈20 ng/m L,8周激素治疗后可达到(449.429±7.325)ng/m L(P〈0.01)。所有患儿均未见激素治疗不良反应表现。结论单纯小阴茎的治疗可直接给予睾酮素或刺激患儿身体自身产生睾酮素,治疗后阴茎的增长效果明显。
出处 《广东医学》 CAS 北大核心 2015年第10期1579-1581,共3页 Guangdong Medical Journal
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